| 31006538 |
Intrinsically Disordered Protein TEX264 Mediates ER-phagy. |
Mol Cell, 2019 Apr 11; [Epub ahead of print] |
Chino H, Hatta T, Natsume T, Mizushima N |
東京大学大学院医学系研究科分子細胞生物学専攻 分子生物学分 千野遥 (0)
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2019/05/08 |
| 30787039 |
COPII vesicles contribute to autophagosomal membranes. |
J Cell Biol, 2019 Feb 20; [Epub ahead of print] |
Shima T, Kirisako H, Nakatogawa H |
東京工業大学・生命理工学院 中戸川 仁 (0)
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2019/04/26 |
| 30810528 |
Two distinct mechanisms target the autophagy-related E3 complex to the pre-autophagosomal structure. |
Elife, 2019 Feb 27; |
Harada K, Kotani T, Kirisako H,... , Nakatogawa H |
東京工業大学・生命理工学院 中戸川 仁 (2)
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2019/04/22 |
| 30911187 |
Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system. |
Nat Struct Mol Biol, 2019 Apr;26(4);289-296, |
Pang Y, Yamamoto H, Sakamoto H, Oku M, Mutungi JK,... , Mizushima N |
東京大学大学院医学系研究科 分子細胞生物学専攻 分子生物学 山本 林 (5)
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2019/04/22 |
| 30911189 |
Atg2 mediates direct lipid transfer between membranes for autophagosome formation. |
Nat Struct Mol Biol, 2019 Mar 25; [Epub ahead of print] |
Osawa T, Kotani T, Kawaoka T, Hirata E, Suzuki K,... , Noda NN |
公益財団法人 微生物化学研究会 大澤拓生 (0)
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2019/03/31 |
| 30783089 |
Suppression of autophagic activity by Rubicon is a signature of aging. |
Nat Commun, 2019 Feb 19;10(1);847, |
Nakamura S, Oba M, Suzuki M, Takahashi A,... , Yoshimori T |
大阪大学 大学院生命機能研究科/高等共創研究院 中村修平 (0)
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2019/03/19 |
| 30451685 |
Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein. |
Elife, 2018 Nov 19; [Epub ahead of print] |
Liu XM, Yamasaki A, Du XM, Coffman VC, Ohsumi Y,... , Du LL |
公益財団法人 微生物化学研究会 山崎章徳 (0)
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2018/11/21 |
| 30309841 |
NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy. |
EMBO Rep, 2018 Oct 11; [Epub ahead of print] |
Furuya N, Kakuta S, Sumiyoshi K, Ando M, Nonaka R,... , Hattori N |
順天堂大学大学院医学研究科 古屋徳彦 (0)
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2018/10/16 |
| 30254161 |
The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation. |
Proc Natl Acad Sci U S A, 2018 Oct 09;115(41);10363-10368, |
Kotani T, Kirisako H, Koizumi M, Ohsumi Y,... , Nakatogawa H |
東京工業大学 生命理工学院 小谷 哲也 (0)
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2018/10/11 |
| 30185561 |
Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex. |
Proc Natl Acad Sci U S A, 2018 Sep 05; [Epub ahead of print] |
Chowdhury S, Otomo C, Leitner A, Ohashi K,... , Otomo T |
スクリプス研究所 大友崇紀 (2)
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2018/10/05 |
| 30093494 |
as a gene required for autophagosome formation. |
J Cell Biol, 2018 Aug 09; [Epub ahead of print] |
Morita K, Hama Y, Izume T, Tamura N, Ueno T,... , Mizushima N |
東京大学大学院医学系研究科分子細胞生物学専攻 守田啓悟 (0)
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2018/08/16 |
| 30030437 |
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure. |
Nat Commun, 2018 Jul 20;9(1);2855, |
Takahashi Y, He H, Tang Z, Hattori T, Liu Y,... , Wang HG |
ペンシルバニア州立大学 高橋 良徳 (0)
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2018/08/10 |
| 29925000 |
The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy. |
Cell Rep, 2018 Jun 19;23(12);3579-3590, |
Furukawa K, Fukuda T, Yamashita SI, Saigusa T,... , Kanki T |
新潟大学大学院医歯学総合研究科・機能制御学分野 古川健太郎 (0)
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2018/07/03 |
| 29868776 |
Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development. |
Brain, 2018 Jun 02; [Epub ahead of print] |
Nahorski MS, Maddirevula S, Ishimura R, Alsahli S,... , Alkuraya FS |
新潟大学大学院医歯学総合研究科 石村亮輔 (0)
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2018/06/13 |
| 29789439 |
Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17. |
J Cell Biol, 2018 May 22; [Epub ahead of print] |
Matsui T, Jiang P, Nakano S, Sakamaki Y,... , Mizushima N |
東北大院・生命科学研究科 松井貴英 (0)
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2018/05/31 |
| 29708272 |
Three Distinct Types of Microautophagy Based on Membrane Dynamics and Molecular Machineries. |
Bioessays, 2018 Apr 30; [Epub ahead of print] |
Oku M, Sakai Y |
京都大学大学院農学研究科 奥 公秀 (0)
|
2018/05/28 |
| 29698392 |
Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane. |
PLoS Genet, 2018 Apr;14(4);e1007334, |
Ukai H, Araki Y, Kira S, Oikawa Y, May AI, Noda T |
大阪大学生命機能研究科（歯学研究科） 鵜飼洋史 (0)
|
2018/05/21 |
| 29255173 |
The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans. |
Nat Cell Biol, 2018 Jan;20(1);81-91, |
Sato M, Sato K, Tomura K, Kosako H, Sato K |
群馬大学・生体調節研究所 佐藤美由紀 (0)
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2018/03/26 |
| 29434298 |
Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice. |
Sci Rep, 2018 Feb 12;8(1);2813, |
Sato S, Uchihara T, Fukuda T, Noda S, Kondo H,... , Hattori N |
順天堂大学 佐藤栄人 (0)
|
2018/03/05 |
| 29475974 |
Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse. |
Development, 2018 Feb 23;145(4); |
Tatsumi T, Takayama K, Ishii S, Yamamoto A,... , Tsukamoto S |
放射線医学総合研究所 技術安全部 塚本 智史 (0)
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2018/03/02 |
| 29339380 |
Negative regulation of the Keap1-Nrf2 pathway by a p62/Sqstm1 splicing variant. |
Mol Cell Biol, 2018 Jan 16; [Epub ahead of print] |
Kageyama S, Saito T, Obata M, Koide RH,... , Komatsu M |
新潟大学大学院 分子生物学講座 蔭山 俊 (0)
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2018/02/04 |
| 29237558 |
Atg7 activates an autophagy-essential ubiquitin-like protein Atg8 through multi-step recognition. |
J Mol Biol, 2017 Dec 10; [Epub ahead of print] |
Yamaguchi M, Satoo K, Suzuki H, Fujioka Y,... , Noda NN |
公益財団法人微生物化学研究会微生物化学研究所 野田 展生 (0)
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2017/12/18 |
| 29113029 |
Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets. |
FEBS Lett, 2017 Nov 07; [Epub ahead of print] |
Tamura N, Nishimura T, Sakamaki Y, Koyama-Honda I,... , Mizushima N |
東大医 田村律人 (0)
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2017/11/14 |
| 28980865 |
Morphometric analysis of autophagy-related structures in Saccharomyces cerevisiae. |
Autophagy, 2017 Oct 05; [Epub ahead of print] |
Kawaoka T, Ohnuki S, Ohya Y, Suzuki K |
東京大学大学院 新領域創成科学研究科 先端生命科学専攻 河岡辰弥 (0)
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2017/10/10 |
| 28838958 |
Evidence for ESCRT- and clathrin-dependent microautophagy. |
J Cell Biol, 2017 Aug 24; [Epub ahead of print] |
Oku M, Maeda Y, Kagohashi Y, Kondo T, Yamada M,... , Sakai Y |
京都大学大学院農学研究科 奥 公秀 (0)
|
2017/08/28 |
| 28743755 |
Ubiquitination of exposed glycoproteins by SCF(FBXO27) directs damaged lysosomes for autophagy. |
Proc Natl Acad Sci U S A, 2017 Jul 25; [Epub ahead of print] |
Yoshida Y, Yasuda S, Fujita T, Hamasaki M,... , Tanaka K |
東京都医学総合研究所 吉田雪子 (0)
|
2017/07/31 |
| 28724756 |
Lysosomal targeting of SIDT2 via multiple YXXΦ motifs is required for SIDT2 function in the process of RNautophagy. |
J Cell Sci, 2017 Jul 19; [Epub ahead of print] |
Contu VR, Hase K, Kozuka-Hata H, Oyama M,... , Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 Contu Raluca (0)
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2017/07/26 |
| 28704456 |
Atg4 plays an important role in efficient expansion of autophagic isolation membranes by cleaving lipidated Atg8 in Saccharomyces cerevisiae. |
PLoS One, 2017;12(7);e0181047, |
Hirata E, Ohya Y, Suzuki K |
東京大学大学院新領域創成科学研究科先端生命科学専攻 平田恵理 (0)
|
2017/07/19 |
| 28683091 |
Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes. |
PLoS Pathog, 2017 Jul;13(7);e1006444, |
Lu SL, Kawabata T, Cheng YL, Omori H, Hamasaki M,... , Yoshimori T |
大阪大学大学院 医学系研究科 遺伝学教室 川端剛 (0)
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2017/07/07 |
| 28460043 |
Cell-free mitochondrial fusion assay detected by specific protease reaction revealed Ca2+ as regulator of mitofusin-dependent mitochondrial fusion. |
J Biochem, 2017 Apr 27; [Epub ahead of print] |
Ishihara N, Maeda M, Ban T, Mihara K |
久留米大学 分子生命科学研究所 石原直忠 (0)
|
2017/06/30 |
| 28628083 |
Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin. |
Nat Cell Biol, 2017 Jul;19(7);856-863, |
Ban T, Ishihara T, Kohno H, Saita S, Ichimura A,... , Ishihara N |
久留米大学 分子生命科学研究所 石原直忠 (0)
|
2017/06/30 |
| 28590904 |
Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole. |
Elife, 2017 Jun 07; |
Tsuji T, Fujimoto M, Tatematsu T, Cheng J, Orii M,... , Fujimoto T |
名大・院医・分子細胞学分野 辻琢磨 (0)
|
2017/06/08 |
| 28361485 |
The Use of Correlative Light-Electron Microscopy (CLEM) to Study PINK1/Parkin-Mediated Mitophagy. |
Methods Mol Biol, 2017 Mar 31; [Epub ahead of print] |
Kishi-Itakura C, Buss F |
University of Cambridge (CIMR) 岸（板倉）千絵子 (0)
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2017/05/24 |
| 28495679 |
Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains. |
EMBO J, 2017 May 11; [Epub ahead of print] |
Nishimura T, Tamura N, Kono N, Shimanaka Y,... , Mizushima N |
東大医 (現 UCL MRC-LMCB) 西村 多喜 (0)
|
2017/05/14 |
| 28492547 |
Autophagy is essential for hearing in mice. |
Cell Death Dis, 2017 May 11;8(5);e2780, |
Fujimoto C, Iwasaki S, Urata S, Morishita H,... , Yamasoba T |
東京大学医学系研究科 外科学専攻 感覚・運動機能講座 藤本千里 (0)
|
2017/05/13 |
| 28483912 |
An in vitro TORC1 kinase assay that recapitulates the Gtr-independent glutamine-responsive TORC1 activation mechanism on yeast vacuoles. |
Mol Cell Biol, 2017 May 08; [Epub ahead of print] |
Tanigawa M, Maeda T |
東京大学・分子細胞生物学研究所 前田達哉 (3)
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2017/06/30 |
| 28320861 |
Recycling of iron via autophagy is critical for the transition from glycolytic to respiratory growth. |
J Biol Chem, 2017 Mar 20; [Epub ahead of print] |
Horie T, Kawamata T, Matsunami M, Ohsumi Y |
日本歯科大学 生命歯学部 堀江 哲郎 (0)
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2017/05/09 |
| 28264932 |
Zinc starvation induces autophagy in yeast. |
J Biol Chem, 2017 Mar 06; [Epub ahead of print] |
Kawamata T, Horie T, Matsunami M, Sasaki M,... , Ohsumi Y |
東京工業大学 科学技術創成研究院 細胞制御工学研究センター 川俣 朋子 (0)
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2017/05/09 |
| 28369861 |
Dissection of ubiquitinated protein degradation by basal autophagy. |
FEBS Lett, 2017 Mar 30; [Epub ahead of print] |
Takayama K, Matsuura A, Itakura E |
千葉大学大学院理学研究院 板倉英祐 (0)
|
2017/04/16 |
| 28039390 |
Lysosomal degradation of intracellular nucleic acids-multiple autophagic pathways. |
J Biochem, 2016 Dec 30; [Epub ahead of print] |
Fujiwara Y, Wada K, Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 藤原 悠紀 (0)
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2017/03/23 |
| 28277980 |
SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells. |
RNA Biol, 2017 Mar 09; [Epub ahead of print] |
Takahashi M, Contu VR, Kabuta C, Hase K,... , Kabuta T |
国立精神・神経医療研究センター 疾病研究第四部 高橋 昌幸 (0)
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2017/03/21 |
| 27846364 |
HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. |
Autophagy, 2016 Nov 15; [Epub ahead of print] |
Watanabe Y, Tsujimura A, Taguchi K, Tanaka M |
京都府立医科大学大学院 医学研究科 渡邊義久 (0)
|
2016/12/07 |
| 27903607 |
Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy. |
J Cell Biol, 2016 Nov 30; [Epub ahead of print] |
Yamashita SI, Jin X, Furukawa K, Hamasaki M,... , Kanki T |
新潟大学大学院医歯学総合研究科機能制御学分野 山下 俊一 (3)
|
2016/12/07 |
| 27885029 |
The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. |
Science, 2016 Nov 25;354(6315);1036-1041, |
Tsuboyama K, Koyama-Honda I, Sakamaki Y, Koike M,... , Mizushima N |
東京大学大学院医学系研究科分子生物学分野 小山-本田郁子 (0)
|
2016/12/01 |
| 27846365 |
Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes. |
Autophagy, 2016 Nov 15; [Epub ahead of print] |
Aizawa S, Contu VR, Fujiwara Y, Hase K, Kikuchi H,... , Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 Ｃｏｎｔｕ Ｒａｌｕｃａ (0)
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2016/11/22 |
| 27818143 |
An Autophagic Flux Probe that Releases an Internal Control. |
Mol Cell, 2016 Oct 25; [Epub ahead of print] |
Kaizuka T, Morishita H, Hama Y, Tsukamoto S,... , Mizushima N |
東京大学 医学系研究科 分子生物学分野 森下 英晃 (0)
|
2016/11/08 |
| 27587839 |
Atg9A trafficking through the recycling endosomes is required for autophagosome formation. |
J Cell Sci, 2016 Oct 15;129(20);3781-3791, |
Imai K, Hao F, Fujita N, Tsuji Y, Oe Y, Araki Y,... , Yoshimori T |
大阪大学大学院 医学系研究科 生命機能研究科 歯学研究科 野田健司 (0)
|
2016/11/05 |
| 27637015 |
Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice. |
Hepatology, 2016 Sep 16; [Epub ahead of print] |
Tanaka S, Hikita H, Tatsumi T, Sakamori R,... , Takehara T |
大阪大学大学院 医学系研究科 竹原 徹郎 (0)
|
2016/11/05 |
| 27693508 |
Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons. |
Dev Cell, 2016 Sep 28; [Epub ahead of print] |
Yoshii SR, Kuma A, Akashi T, Hara T, Yamamoto A,... , Mizushima N |
東京大学医学系研究科 久万亜紀子、吉井紗織 (0)
|
2016/10/10 |
| 27545674 |
Biallelic Variants in UBA5 Link Dysfunctional UFM1?Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy. |
Am J Hum Genet, 2016 Sep 1;99(3);683-94, |
Muona M, Ishimura R, Laari A, Ichimura Y,... , Komatsu M |
新潟大学大学院医歯学総合研究科 石村亮輔 (0)
|
2016/09/29 |