| 28460043 |
Cell-free mitochondrial fusion assay detected by specific protease reaction revealed Ca2+ as regulator of mitofusin-dependent mitochondrial fusion. |
J Biochem, 2017 Apr 27; [Epub ahead of print] |
Ishihara N, Maeda M, Ban T, Mihara K |
久留米大学 分子生命科学研究所 石原直忠 (0)
|
2017/06/30 |
| 28628083 |
Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin. |
Nat Cell Biol, 2017 Jul;19(7);856-863, |
Ban T, Ishihara T, Kohno H, Saita S, Ichimura A,... , Ishihara N |
久留米大学 分子生命科学研究所 石原直忠 (0)
|
2017/06/30 |
| 28590904 |
Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole. |
Elife, 2017 Jun 07; |
Tsuji T, Fujimoto M, Tatematsu T, Cheng J, Orii M,... , Fujimoto T |
名大・院医・分子細胞学分野 辻琢磨 (0)
|
2017/06/08 |
| 28361485 |
The Use of Correlative Light-Electron Microscopy (CLEM) to Study PINK1/Parkin-Mediated Mitophagy. |
Methods Mol Biol, 2017 Mar 31; [Epub ahead of print] |
Kishi-Itakura C, Buss F |
University of Cambridge (CIMR) 岸（板倉）千絵子 (0)
|
2017/05/24 |
| 28495679 |
Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains. |
EMBO J, 2017 May 11; [Epub ahead of print] |
Nishimura T, Tamura N, Kono N, Shimanaka Y,... , Mizushima N |
東大医 (現 UCL MRC-LMCB) 西村 多喜 (0)
|
2017/05/14 |
| 28492547 |
Autophagy is essential for hearing in mice. |
Cell Death Dis, 2017 May 11;8(5);e2780, |
Fujimoto C, Iwasaki S, Urata S, Morishita H,... , Yamasoba T |
東京大学医学系研究科 外科学専攻 感覚・運動機能講座 藤本千里 (0)
|
2017/05/13 |
| 28483912 |
An in vitro TORC1 kinase assay that recapitulates the Gtr-independent glutamine-responsive TORC1 activation mechanism on yeast vacuoles. |
Mol Cell Biol, 2017 May 08; [Epub ahead of print] |
Tanigawa M, Maeda T |
東京大学・分子細胞生物学研究所 前田達哉 (3)
|
2017/06/30 |
| 28320861 |
Recycling of iron via autophagy is critical for the transition from glycolytic to respiratory growth. |
J Biol Chem, 2017 Mar 20; [Epub ahead of print] |
Horie T, Kawamata T, Matsunami M, Ohsumi Y |
日本歯科大学 生命歯学部 堀江 哲郎 (0)
|
2017/05/09 |
| 28264932 |
Zinc starvation induces autophagy in yeast. |
J Biol Chem, 2017 Mar 06; [Epub ahead of print] |
Kawamata T, Horie T, Matsunami M, Sasaki M,... , Ohsumi Y |
東京工業大学 科学技術創成研究院 細胞制御工学研究センター 川俣 朋子 (0)
|
2017/05/09 |
| 28369861 |
Dissection of ubiquitinated protein degradation by basal autophagy. |
FEBS Lett, 2017 Mar 30; [Epub ahead of print] |
Takayama K, Matsuura A, Itakura E |
千葉大学大学院理学研究院 板倉英祐 (0)
|
2017/04/16 |
| 28039390 |
Lysosomal degradation of intracellular nucleic acids-multiple autophagic pathways. |
J Biochem, 2016 Dec 30; [Epub ahead of print] |
Fujiwara Y, Wada K, Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 藤原 悠紀 (0)
|
2017/03/23 |
| 28277980 |
SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells. |
RNA Biol, 2017 Mar 09; [Epub ahead of print] |
Takahashi M, Contu VR, Kabuta C, Hase K,... , Kabuta T |
国立精神・神経医療研究センター 疾病研究第四部 高橋 昌幸 (0)
|
2017/03/21 |
| 27846364 |
HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. |
Autophagy, 2016 Nov 15; [Epub ahead of print] |
Watanabe Y, Tsujimura A, Taguchi K, Tanaka M |
京都府立医科大学大学院 医学研究科 渡邊義久 (0)
|
2016/12/07 |
| 27903607 |
Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy. |
J Cell Biol, 2016 Nov 30; [Epub ahead of print] |
Yamashita SI, Jin X, Furukawa K, Hamasaki M,... , Kanki T |
新潟大学大学院医歯学総合研究科機能制御学分野 山下 俊一 (3)
|
2016/12/07 |
| 27885029 |
The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. |
Science, 2016 Nov 25;354(6315);1036-1041, |
Tsuboyama K, Koyama-Honda I, Sakamaki Y, Koike M,... , Mizushima N |
東京大学大学院医学系研究科分子生物学分野 小山-本田郁子 (0)
|
2016/12/01 |
| 27846365 |
Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes. |
Autophagy, 2016 Nov 15; [Epub ahead of print] |
Aizawa S, Contu VR, Fujiwara Y, Hase K, Kikuchi H,... , Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 Ｃｏｎｔｕ Ｒａｌｕｃａ (0)
|
2016/11/22 |
| 27818143 |
An Autophagic Flux Probe that Releases an Internal Control. |
Mol Cell, 2016 Oct 25; [Epub ahead of print] |
Kaizuka T, Morishita H, Hama Y, Tsukamoto S,... , Mizushima N |
東京大学 医学系研究科 分子生物学分野 森下 英晃 (0)
|
2016/11/08 |
| 27587839 |
Atg9A trafficking through the recycling endosomes is required for autophagosome formation. |
J Cell Sci, 2016 Oct 15;129(20);3781-3791, |
Imai K, Hao F, Fujita N, Tsuji Y, Oe Y, Araki Y,... , Yoshimori T |
大阪大学大学院 医学系研究科 生命機能研究科 歯学研究科 野田健司 (0)
|
2016/11/05 |
| 27637015 |
Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice. |
Hepatology, 2016 Sep 16; [Epub ahead of print] |
Tanaka S, Hikita H, Tatsumi T, Sakamori R,... , Takehara T |
大阪大学大学院 医学系研究科 竹原 徹郎 (0)
|
2016/11/05 |
| 27693508 |
Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons. |
Dev Cell, 2016 Sep 28; [Epub ahead of print] |
Yoshii SR, Kuma A, Akashi T, Hara T, Yamamoto A,... , Mizushima N |
東京大学医学系研究科 久万亜紀子、吉井紗織 (0)
|
2016/10/10 |
| 27545674 |
Biallelic Variants in UBA5 Link Dysfunctional UFM1?Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy. |
Am J Hum Genet, 2016 Sep 1;99(3);683-94, |
Muona M, Ishimura R, Laari A, Ichimura Y,... , Komatsu M |
新潟大学大学院医歯学総合研究科 石村亮輔 (0)
|
2016/09/29 |
| 27404361 |
The Intrinsically Disordered Protein Atg13 Mediates Supramolecular Assembly of Autophagy Initiation Complexes. |
Dev Cell, 2016 Jul 11;38(1);86-99, |
Yamamoto H, Fujioka Y, Suzuki SW, Noshiro D,... , Ohsumi Y |
東京大学 医学系研究科 分子生物学分野 山本 林 (0)
|
2016/07/25 |
| 27345495 |
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. |
Nat Commun, 2016;12030, |
Saito T, Ichimura Y, Taguchi K, Suzuki T,... , Komatsu M |
新潟大学大学院医歯学総合研究科 齊藤哲也 (0)
|
2016/07/13 |
| 27340123 |
Autophagosome-lysosome fusion in neurons requires INPP5E, a protein associated with Joubert?syndrome. |
EMBO J, 2016 Jun 23; [Epub ahead of print] |
Hasegawa J, Iwamoto R, Otomo T, Nezu A,... , Yoshimori T |
大阪大学大学院生命機能研究科 長谷川 純矢 (0)
|
2016/07/05 |
| 27320913 |
Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates. |
Cell Rep, 2016 Jun 15; [Epub ahead of print] |
Yamasaki A, Watanabe Y, Adachi W, Suzuki K,... , Noda NN |
公益財団法人微生物化学研究会 微生物化学研究所 山崎 章徳 (1)
|
2016/06/22 |
| 26929408 |
Structural and functional analysis of a novel interaction motif within UFM1-activating enzyme 5 (UBA5) required for binding to ubiquitin-like proteins and ufmylation. |
J Biol Chem, 2016 Feb 29; [Epub ahead of print] |
Habisov S, Huber J, Ichimura Y, Akutsu M,... , Kirkin V |
新潟大学大学院医歯学総合研究科 一村義信 (0)
|
2016/04/21 |
| 26902585 |
Differing susceptibility to autophagic degradation of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1. |
Autophagy, 2016 Feb;12(2);312-26, |
Hirano S, Uemura T, Annoh H, Fujita N, Waguri S,... , Fukuda M |
東北大学生命科学研究科 藤田尚信 (0)
|
2016/04/12 |
| 27046251 |
Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. |
Autophagy, 2016 Mar 3;12(3);565-78, |
Aizawa S, Fujiwara Y, Contu VR, Hase K,... , Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 株田智弘 (0)
|
2016/04/08 |
| 26823550 |
Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD. |
J Am Soc Nephrol, 2016 Jan 28; [Epub ahead of print] |
Yamamoto-Nonaka K, Koike M, Asanuma K, Takagi M,... , Tomino Y |
順天堂大学医学部 山本 香苗 (0)
|
2016/02/08 |
| 26682926 |
Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity. |
Biochem Biophys Res Commun, 2015 Dec 9; [Epub ahead of print] |
Mehanna S, Suzuki C, Shibata M, Sunabori T,... , Ohmuraya M |
熊本大学生命資源研究・支援センター 大村谷昌樹 (0)
|
2015/12/25 |
| 26687600 |
Structural Basis of the Differential Function of the Two C.?elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. |
Mol Cell, 2015 Dec 17;60(6);914-29, |
Wu F, Watanabe Y, Guo XY, Qi X, Wang P, Zhao HY,... , Zhang H |
微生物化学研究会・微生物化学研究所 野田 展生 (0)
|
2015/12/23 |
| 25619926 |
A role for the ancient SNARE syntaxin 17 in regulating mitochondrial division. |
Dev Cell, 2015 Feb 9;32(3);304-17, |
Arasaki K, Shimizu H, Mogari H, Nishida N,... , Tagaya M |
東京薬科大学・生命科学部 新崎恒平 (0)
|
2015/12/16 |
| 26609069 |
Dynamic relocation of the TORC1-Gtr1/2-Ego1/2/3 complex is regulated by Gtr1 and Gtr2. |
Mol Biol Cell, 2015 Nov 25; [Epub ahead of print] |
Kira S, Kumano Y, Ukai H, Takeda E, Matsuura A,... , Noda T |
大阪大学大学院歯学研究科口腔科学フロンティアセンター 吉良新太郎 (0)
|
2015/12/16 |
| 26483381 |
Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells. |
J Cell Sci, 2015 Dec 1;128(23);4453-61, |
Eino A, Kageyama S, Uemura T, Annoh H, Saito T,... , Komatsu M |
新潟大学医歯学系 蔭山 俊 (0)
|
2015/12/15 |
| 26213203 |
Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. |
Autophagy, 2015;11(9);1471-83, |
Hieke N, Loffler AS, Kaizuka T, Berleth N,... , Stork B |
東京大学 大学院医学系研究科 貝塚 剛志 (0)
|
2015/12/12 |
| 26644405 |
Atg13 is essential for autophagy and cardiac development in mice. |
Mol Cell Biol, 2015 Dec 7; [Epub ahead of print] |
Kaizuka T, Mizushima N |
東京大学 大学院医学系研究科 貝塚 剛志 (0)
|
2015/12/12 |
| 26572622 |
Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration. |
J Cell Biol, 2015 Nov 16; [Epub ahead of print] |
Wakatsuki S, Furuno A, Ohshima M, Araki T |
国立精神・神経医療研究センター・神経研究所 若月修二 (0)
|
2015/11/24 |
| 26442587 |
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy. |
J Biol Chem, 2015 Oct 6; [Epub ahead of print] |
Yamamoto H, Shima T, Yamaguchi M, Mochizuki Y,... , Ohsumi Y |
東京工業大学 フロンティア研究機構 山本 林 (0)
|
2015/10/14 |
| 26438722 |
Phospholipid methylation controls Atg32-mediated mitophagy and Atg8 recycling. |
EMBO J, 2015 Oct 5; [Epub ahead of print] |
Sakakibara K, Eiyama A, Suzuki SW,... , Okamoto K |
大阪大学大学院生命機能研究科 岡本浩二 (0)
|
2015/10/08 |
| 26296886 |
Protein N-terminal Acetylation by NatA Is Critical for Selective Mitochondria Degradation. |
J Biol Chem, 2015 Aug 21; [Epub ahead of print] |
Eiyama A, Okamoto K |
大阪大学大学院 生命機能研究科 英山 明慶 (0)
|
2015/08/28 |
| 26038313 |
RNautophagy/DNautophagy possesses selectivity for RNA/DNA substrates. |
Nucleic Acids Res, 2015 Jul 27;43(13);6439-49, |
Hase K, Fujiwara Y, Kikuchi H, Aizawa S, Hakuno F,... , Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 長谷勝徳 (0)
|
2015/08/05 |
| 26146385 |
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation. |
Nat Commun, 2015;7527, |
Murakawa T, Yamaguchi O, Hashimoto A, Hikoso S,... , Otsu K |
キングスカレッジロンドン医学部 大津 欣也 (0)
|
2015/07/29 |
| 26061644 |
A defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis. |
Autophagy, 2015 Jun 10; [Epub ahead of print] |
Maeda Y, Oku M, Sakai Y |
京都大学大学院 農学研究科 応用生命科学専攻 奥 公秀 (0)
|
2015/06/12 |
| 26030876 |
Structure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiation. |
Nat Struct Mol Biol, 2015 Jun 1; [Epub ahead of print] |
Suzuki H, Kaizuka T, Mizushima N, Noda NN |
微生物化学研究所 鈴木浩典 (0)
|
2015/06/10 |
| 26040717 |
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus. |
Nature, 2015 Jun 3; [Epub ahead of print] |
Mochida K, Oikawa Y, Kimura Y, Kirisako H,... , Nakatogawa H |
東京工業大学 生命理工学研究科 持田 啓佑 (0)
|
2015/06/10 |
| 25948417 |
Atg1 family kinases in autophagy initiation. |
Cell Mol Life Sci, 2015 May 7; [Epub ahead of print] |
Noda NN, Fujioka Y |
公益財団法人微生物化学研究会 微生物化学研究所 野田 展生 (0)
|
2015/05/09 |
| 25923949 |
Atg8 is involved in endosomal and phagosomal acidification in the parasitic protist Entamoeba histolytica. |
Cell Microbiol, 2015 Apr 29; [Epub ahead of print] |
Picazarri K, Nakada-Tsukui K, Tsuboi K,... , Nozaki T |
国立感染症研究所 津久井久美子 (0)
|
2015/05/08 |
| 25900611 |
Yeast nitrogen utilization in the phyllosphere during plant lifespan under regulation of autophagy. |
Sci Rep, 2015;9719, |
Shiraishi K, Oku M, Kawaguchi K, Uchida D,... , Sakai Y |
京都大学大学院農学研究科応用生命科学専攻 白石晃將 (0)
|
2015/04/27 |
| 25772617 |
An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding. |
Biochem Biophys Res Commun, 2015 Mar 13; [Epub ahead of print] |
Fujiwara Y, Hase K, Wada K, Kabuta T |
国立精神・神経医療研究センター 神経研究所 疾病研究第四部 藤原悠紀 (0)
|
2015/04/14 |
| 25831013 |
Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways. |
Autophagy, 2015 Feb;11(2);332-43, |
Hirota Y, Yamashita S, Kurihara Y, Jin X,... , Kanki T |
新潟大学大学院医歯学総合研究科 神吉智丈 (0)
|
2015/04/09 |