Proteolysis Forum
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全463件中　101-150件表示
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PubMedID Title Journal Author Re updated
25527407Ubiquitin acetylation inhibits polyubiquitin chain elongation.EMBO Rep, 2014 Dec 19; [Epub ahead of print]Ohtake F, Saeki Y, ..., Tanaka K, Kanno J 0 2015/01/03
25551774Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion.Autophagy, 2014 Dec 31; [Epub ahead of print]Brandstaetter H, Kishi-Itakura C, ..., Manstein DJ, Buss F 0 2015/01/03
25435427The autophagy pathway maintained signaling crosstalk with the Keap1-Nrf2 system through p62 in auditory cells under oxidative stress.Cell Signal, 2015 Feb;27(2);382-93, Hayashi K, Dan K, ..., Kanzaki S, Ogawa K 0 2015/01/01
25485838Mutations in the deubiquitinase gene USP8 cause Cushing's disease.Nat Genet, 2014 Dec 8; [Epub ahead of print]Reincke M, Sbiera S, ..., Fassnacht M, Komada M 0 2014/12/12
25468960Bulk RNA degradation by nitrogen starvation-induced autophagy in yeast.EMBO J, 2014 Dec 2; [Epub ahead of print]Huang H, Kawamata T, ..., Ohsumi Y, Fukusaki E 1 2014/12/05
25281559Hrr25 phosphorylates the autophagic receptor Atg34 to promote vacuolar transport of α-mannosidase under nitrogen starvation conditions.FEBS Lett, 2014 Oct 2; [Epub ahead of print]Mochida K, Ohsumi Y, Nakatogawa H 0 2014/10/17
25287303Hrr25 triggers selective autophagy-related pathways by phosphorylating receptor proteins.J Cell Biol, 2014 Oct 13;207(1);91-105, Tanaka C, Tan LJ, ..., Ohsumi Y, Nakatogawa H 0 2014/10/17
25109892The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy.Biochim Biophys Acta, 2014 Aug 7; [Epub ahead of print]  0 2014/08/29
25077633Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition.Sci Rep, 2014;5896, Maharjan S, Oku M, ..., Hoseki J, Sakai Y 0 2014/08/06
25036706Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.J Clin Invest, 2014 Aug 1;124(8);3634-44,  0 2014/08/05
25023287Stearoyl-CoA desaturase 1 activity is required for autophagosome formation.J Biol Chem, 2014 Jul 14; [Epub ahead of print]Ogasawara Y, Itakura E, ..., Mizukami T, Yamamoto A 0 2014/07/31
25049227Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway.J Biol Chem, 2014 Jul 21; [Epub ahead of print]Kageyama S, Sou YS, ..., Tanaka K, Komatsu M 0 2014/07/30
25052093Ultrastructural analysis of autophagosome organization using mammalian autophagy-deficient cells.J Cell Sci, 2014 Jul 22; [Epub ahead of print]Kishi-Itakura C, Koyama-Honda I, Itakura E, Mizushima N 1 2014/07/29
25046117Reciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy.Autophagy, 2014 Jun 30;10(9); [Epub ahead of print]Kira S, Tabata K, ..., Yoshimori T, Noda T 0 2014/07/25
24838945The Tor and Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32.J Cell Sci, 2014 May 16; [Epub ahead of print]Aihara M, Jin X, ..., Kang D, Kanki T 0 2014/06/05
24793651Structural basis of starvation-induced assembly of the autophagy initiation complex.Nat Struct Mol Biol, 2014 May 4; [Epub ahead of print]Fujioka Y, Suzuki SW, ..., Ohsumi Y, Noda NN 0 2014/05/07
24784582Ubiquitin is phosphorylated by PINK1 to activate parkin.Nature, 2014 Apr 30; [Epub ahead of print]Koyano F, Okatsu K, ..., Tanaka K, Matsuda N 0 2014/05/04
24719330Dennd3 Functions as a Guanine Nucleotide Exchange Factor for Small GTPase Rab12 in Mouse Embryonic Fibroblasts.J Biol Chem, 2014 Apr 9; [Epub ahead of print]Matsui T, Noguchi K, Fukuda M 0 2014/04/28
24598877Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome.Nat Commun, 2014;3396, Pack CG, Yukii H, ..., Tanaka K, Saeki Y 0 2014/04/24
23898401Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4.Elife, 2013;e00953, Foresti O, Ruggiano A, ..., Ejsing CS, Carvalho P 0 2014/04/24
24668264Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.EMBO Rep, 2014 Mar 25; [Epub ahead of print]Lystad AH, Ichimura Y, ..., Komatsu M, Simonsen A 0 2014/04/11
24492006Dissection of the role of p62/Sqstm1 in activation of Nrf2 during xenophagy.FEBS Lett, 2014 Mar 3;588(5);822-8,  0 2014/04/11
24591649A cluster of thin tubular structures mediates transformation of the ER to autophagic isolation membrane.Mol Cell Biol, 2014 Mar 3; [Epub ahead of print]Uemura T, Yamamoto M, ..., Komatsu M, Waguri S 0 2014/04/03
24681842Fluorescence-based visualization of autophagic activity predicts mouse embryo viability.Sci Rep, 2014;4533, Tsukamoto S, Hara T, ..., Sato K, Kokubo T 0 2014/04/02
24394643Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids.Autophagy, 2014 Jan 3;10(3); [Epub ahead of print]Sahani MH, Itakura E, Mizushima N 0 2014/03/26
24530295Mitochondrial ER Contacts Are Crucial for Mitophagy in Yeast.Dev Cell, 2014 Feb 24;28(4);450-8,  0 2014/03/26
24469399Mechanism Underlying IκB Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex.Mol Cell Biol, 2014 Apr;34(7);1322-35, Fujita H, Rahighi S, ..., Wakatsuki S, Iwai K 0 2014/03/25
24634492IFN-γ or IFN-α Ameliorates Chronic Proliferative Dermatitis by Inducing Expression of Linear Ubiquitin Chain Assembly Complex.J Immunol, 2014 Mar 14; [Epub ahead of print]Tamiya H, Terao M, ..., Yoshikawa H, Iwai K 0 2014/03/24
24461064Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.Genes Cells, 2014 Mar;19(3);254-272, Takiuchi T, Nakagawa T, ..., Kimura T, Iwai K 0 2014/03/24
24626240Proteomic Profiling of Autophagosome Cargo in Saccharomyces cerevisiae.PLoS One, 2014;9(3);e91651, Suzuki K, Nakamura S, ..., Inagaki F, Ohsumi Y 0 2014/03/20
24239290Autoadaptive ER-associated degradation defines a preemptive unfolded protein response pathway.Mol Cell, 2013 Dec 26;52(6);783-93,  0 2014/02/18
24440502Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase.Mol Cell, 2014 Jan 14; [Epub ahead of print]  0 2014/02/07
24492518Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries.Nat Commun, 2014 Feb 4;3207, Cheng J, Fujita A, ..., Ohsumi Y, Fujimoto T 0 2014/02/05
24416124Lysosomal interaction of akt with phafin2: a critical step in the induction of autophagy.PLoS One, 2014;9(1);e79795, Matsuda-Lennikov M, Suizu F, ..., Iwanaga T, Noguchi M 0 2014/01/27
24451648PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation.Autophagy, 2014 Jan 21;10(4); [Epub ahead of print]Furuya N, Ikeda SI, ..., Hattori N, Ueno T 0 2014/01/27
24075993The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells.Cell Rep, 2013 Oct 17;5(1);224-36,  0 2014/01/24
24357321CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.Science, 2013 Dec 20;342(6165);1518-21, Yu C, Zhang YL, ..., Sun QY, Fan HY 0 2014/01/17
23287719A strategy for modulation of enzymes in the ubiquitin system.Science, 2013 Feb 1;339(6119);590-5, Ernst A, Avvakumov G, ..., Dhe-Paganon S, Sidhu SS 0 2014/01/14
24098148Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway.PLoS Genet, 2013;9(10);e1003845, Inoue K, Rispoli J, ..., Klann E, Abeliovich A 0 2014/01/03
24324262Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37.J Biol Chem, 2013 Dec 9; [Epub ahead of print]Tanno H, Shigematsu T, ..., Tanaka T, Komada M 0 2013/12/25
23549786Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae.J Cell Sci, 2013 Jun 1;126(Pt 11);2534-44, Suzuki K, Akioka M, ..., Yamamoto H, Ohsumi Y 0 2013/12/11
23839276Direct uptake and degradation of DNA by lysosomes.Autophagy, 2013 Aug;9(8);1167-71, Fujiwara Y, Kikuchi H, ..., Wada K, Kabuta T 0 2013/12/10
23291500Discovery of a novel type of autophagy targeting RNA.Autophagy, 2013 Mar;9(3);403-9, Fujiwara Y, Furuta A, ..., Wada K, Kabuta T 0 2013/12/10
24089205Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites.Nature, 2013 Oct 10;502(7470);254-7, Tang Z, Lin MG, ..., Franco B, Zhong Q 0 2013/11/13
23921551Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury.EMBO J, 2013 Aug 28;32(17);2336-47, Maejima I, Takahashi A, ..., Isaka Y, Yoshimori T 0 2013/10/09
23991809Proteomics Analysis Reveals a Highly Heterogeneous Proteasome Composition and the Post-translational Regulation of Peptidase Activity under Pathogen Signaling in Plants.J Proteome Res, 2013 Sep 20; [Epub ahead of print]Sun HH, Fukao Y, ..., Sato T, Yamaguchi J 0 2013/10/01
23897086Casein kinase 2 is essential for mitophagy.EMBO Rep, 2013 Aug 30;14(9);788-94, Kanki T, Kurihara Y, ..., Uchiumi T, Kang D 0 2013/09/25
24011591Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy.Mol Cell, 2013 Sep 12;51(5);618-31,  0 2013/09/25
23942237Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.EMBO J, 2013 Sep 11;32(18);2463-76, Sasaki Y, Sano S, ..., Kurosaki T, Iwai K 0 2013/09/15
23435086De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood.Nat Genet, 2013 Apr;45(4);445-9, 449e1, Saitsu H, Nishimura T, ..., Mizushima N, Matsumoto N 0 2013/09/11
23744068Differential Contribution of Insulin and Amino Acids to the mTORC1-Autophagy Pathway in the Liver and Muscle.J Biol Chem, 2013 Jul 19;288(29);21074-81, Naito T, Kuma A, Mizushima N 0 2013/09/07
23930225The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis.Elife, 2013;e00947, Ge L, Melville D, Zhang M, Schekman R 0 2013/09/06
23286108Parametric dictionary learning for modeling EAP and ODF in diffusion MRI.Med Image Comput Comput Assist Interv, 2012;15(Pt 3);10-7, Merlet S, Caruyer E, Deriche R 0 2013/09/06
23954414Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism.Cell, 2013 Aug 14; [Epub ahead of print]  0 2013/08/21
23286110Geodesic shape-based averaging.Med Image Comput Comput Assist Interv, 2012;15(Pt 3);26-33, Cardoso MJ, Winston G, ..., Duncan J, Ourselin S 0 2013/08/21
23935533Calpain-6 deficiency promotes skeletal muscle development and regeneration.PLoS Genet, 2013 Aug;9(8);e1003668, Tonami K, Hata S, ..., Kurihara H, Sorimachi H 65535 2013/08/21
23940117Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity.J Cell Biol, 2013 Aug 19;202(4);685-98, Tamura N, Oku M, ..., Inagaki F, Sakai Y 0 2013/08/21
22078875Autophagy: renovation of cells and tissues.Cell, 2011 Nov 11;147(4);728-41, Mizushima N, Komatsu M 65535 2013/08/14
23827681OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.Cell, 2013 Jul 3;154(1);169-84,  0 2013/08/02
23286107Accelerated diffusion spectrum imaging with compressed sensing using adaptive dictionaries.Med Image Comput Comput Assist Interv, 2012;15(Pt 3);1-9, Bilgic B, Setsompop K, ..., Wald LL, Adalsteinsson E 0 2013/07/25
23317502Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways.Mol Cell, 2013 Feb 7;49(3);487-98,  0 2013/07/05
23417015End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1.EMBO J, 2013 Mar 20;32(6);805-15, Lescasse R, Pobiega S, Callebaut I, Marcand S 0 2013/07/05
23726910The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification.Biochem Biophys Res Commun, 2013 Jun 28;436(2);223-9,  0 2013/07/05
23791384PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone.Cell, 2013 Jun 19; [Epub ahead of print]  0 2013/07/01
23754282Parkin catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.J Biol Chem, 2013 Jun 10; [Epub ahead of print]Iguchi M, Kujuro Y, ..., Tanaka K, Matsuda N 0 2013/06/30
23354051Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.Nature, 2013 Feb 21;494(7437);375-9, Song R, Peng W, ..., Cao CM, Xiao RP 0 2013/06/18
23727017MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2.Mol Cell, 2013 May 29; [Epub ahead of print]  0 2013/06/04
23453757Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins.Cell, 2013 Mar 28;153(1);206-15,  0 2013/05/10
23452853Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination.Cell, 2013 Feb 28;152(5);1051-64,  0 2013/04/26
23453807The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO.Mol Cell, 2013 Mar 7;49(5);908-21,  0 2013/04/16
22895187Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.Nature, 2012 Aug 30;488(7413);665-9, Koo BK, Spit M, ..., Maurice MM, Clevers H 0 2012/12/29
22575959ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.Nature, 2012 May 10;485(7397);195-200, Hao HX, Xie Y, ..., Serluca FC, Cong F 0 2012/12/29
23142983Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.Nat Struct Mol Biol, 2012 Dec;19(12);1250-6, Yamaguchi M, Matoba K, ..., Noda NN, Inagaki F 0 2012/12/20
23217709The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes.Cell, 2012 Dec 7;151(6);1256-69,  1 2012/12/13
22682742Structural Insights into Atg10-Mediated Formation of the Autophagy-Essential Atg12-Atg5 Conjugate.Structure, 2012 Jun 6; [Epub ahead of print]Yamaguchi M, Noda NN, ..., Ohsumi Y, Inagaki F 0 2012/06/26
22308378Mitochondrial ubiquitin ligase MITOL blocks S-nitrosylated MAP1B-light chain 1-mediated mitochondrial dysfunction and neuronal cell death.Proc Natl Acad Sci U S A, 2012 Jan 30; [Epub ahead of print]Yonashiro R, Kimijima Y, ..., Inatome R, Yanagi S 0 2012/02/09
22049402Doxorubicin-induced glomerulosclerosis with proteinuria in GFP-GABARAP transgenic mice.Am J Physiol Renal Physiol, 2012 Feb;302(3);F380-9, Takagi-Akiba M, Asanuma K, ..., Ueno T, Tomino Y 0 2012/02/05
22298428The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane.Mol Biol Cell, 2012 Feb 1; [Epub ahead of print]Tanno H, Yamaguchi T, ..., Ishido S, Komada M 0 2012/02/03
22275429Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.J Cell Sci, 2012 Jan 24; [Epub ahead of print]Itakura E, Kishi-Itakura C, Koyama-Honda I, Mizushima N 0 2012/02/01
22219374Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.Mol Biol Cell, 2012 Jan 4; [Epub ahead of print]Velikkakath AK, Nishimura T, ..., Ishihara N, Mizushima N 2 2012/01/26
21966472Yeast methylotrophy and autophagy in a methanol-oscillating environment on growing Arabidopsis thaliana leaves.PLoS One, 2011;6(9);e25257, Kawaguchi K, Yurimoto H, Oku M, Sakai Y 0 2012/01/16
22157017Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast.J Biol Chem, 2011 Dec 7; [Epub ahead of print]Kurihara Y, Kanki T, ..., Uchiumi T, Kang D 0 2011/12/21
22055191Structural basis of atg8 activation by a homodimeric e1, atg7.Mol Cell, 2011 Nov 4;44(3);462-75, Noda NN, Satoo K, ..., Ohsumi Y, Inagaki F 0 2011/11/11
21839922Selective Autophagy Regulates Insertional Mutagenesis by the Ty1 Retrotransposon in Saccharomyces cerevisiae.Dev Cell, 2011 Aug 16;21(2);358-65, Suzuki K, Morimoto M, Kondo C, Ohsumi Y 0 2011/08/30
21757540Phosphorylation of Ser114 on Atg32 mediates mitophagy.Mol Biol Cell, 2011 Jul 14; [Epub ahead of print]Aoki Y, Kanki T, ..., Uchiumi T, Kang D 0 2011/07/19
21616915Calpain-7 binds to CHMP1B at its second {alpha}-helical region and forms a ternary complex with IST1.J Biochem, 2011 May 25; [Epub ahead of print]Maemoto Y, Osako Y, ..., Shibata H, Maki M 0 2011/05/31
21498569Autophagy-deficient mice develop multiple liver tumors.Genes Dev, 2011 Apr 15;25(8);795-800, Takamura A, Komatsu M, ..., Tanaka K, Mizushima N 0 2011/05/09
21304510The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice.Nat Commun, 2011 Feb;181, Tatsumi K, Yamamoto-Mukai H, ..., Yamamoto M, Komatsu M 0 2011/04/15
21454557Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.J Biol Chem, 2011 Mar 18; [Epub ahead of print]Yoshii SR, Kishi C, Ishihara N, Mizushima N 0 2011/04/14
21444722Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells.Mol Cell Biol, 2011 Mar 28; [Epub ahead of print]Asano T, Komatsu M, ..., Mizushima N, Iwai K 0 2011/04/13
21471734Liver autophagy contributes to the maintenance of blood glucose and amino acid levels.Autophagy, 2011 Jul 1;7(7); [Epub ahead of print]Ezaki J, Matsumoto N, ..., Kominami E, Ueno T 0 2011/04/12
21389113Non-SCF type F-box protein Roy1/Ymr258c interacts with a Rab5-like GTPase Ypt52 and inhibits Ypt52 function.Mol Biol Cell, 2011 Mar 9; [Epub ahead of print]Liu Y, Nakatsukasa K, ..., Mimura S, Kamura T 0 2011/04/11
21406564Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1.J Cell Sci, 2011 Apr 15;124(Pt 8);1214-23, Tonami K, Kurihara Y, ..., Sorimachi H, Kurihara H 0 2011/04/04
21338355Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25.J Neurochem, 2011 Feb 21; [Epub ahead of print]Sato K, Minegishi S, ..., Saido TC, Hisanaga SI 0 2011/03/28
21383079OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.J Cell Biol, 2011 Mar 7;192(5);839-53, Itoh T, Kanno E, ..., Waguri S, Fukuda M 0 2011/03/20
21364763Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction.PLoS One, 2011;6(2);e17412, Suzuki SW, Onodera J, Ohsumi Y 0 2011/03/07
21295580Non-Proteolytic Functions of Calpain-3 in Sarcoplasmic Reticulum in Skeletal Muscles.J Mol Biol, 2011 Feb 3; [Epub ahead of print]Ojima K, Ono Y, ..., Granzier H, Sorimachi H 0 2011/02/28
21333342Crucial role for autophagy in degranulation of mast cells.J Allergy Clin Immunol, 2011 Feb 17; [Epub ahead of print]Ushio H, Ueno T, ..., Okumura K, Nakano H 0 2011/02/25
21173115Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.J Cell Biol, 2010 Dec 27;191(7);1367-80, Tanaka A, Cleland MM, ..., Karbowski M, Youle RJ 0 2011/02/11
21264228Mieap, a p53-Inducible Protein, Controls Mitochondrial Quality by Repairing or Eliminating Unhealthy Mitochondria.PLoS One, 2011;6(1);e16060, Kitamura N, Nakamura Y, ..., Ichinose S, Arakawa H 0 2011/01/27
21264221Possible Existence of Lysosome-Like Organella within Mitochondria and Its Role in Mitochondrial Quality Control.PLoS One, 2011;6(1);e16054, Miyamoto Y, Kitamura N, ..., Ichinose S, Arakawa H 0 2011/01/27
21220506p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.J Cell Biol, 2011 Jan 10;192(1);17-27, Itakura E, Mizushima N 0 2011/01/17
21098295From the Cover: Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.Proc Natl Acad Sci U S A, 2010 Dec 7;107(49);20992-7, Bohn S, Beck F, ..., Baumeister W, Nickell S 0 2010/12/09
20956561Endocytosis of the Aspartic Acid/Glutamic Acid Transporter Dip5 Is Triggered by Substrate-Dependent Recruitment of the Rsp5 Ubiquitin Ligase via the Arrestin-Like Protein Aly2.Mol Cell Biol, 2010 Dec;30(24);5598-607, Hatakeyama R, Kamiya M, Takahara T, Maeda T 0 2010/11/25
21045113Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris.J Cell Sci, 2010 Nov 2; [Epub ahead of print]Tamura N, Oku M, Sakai Y 0 2010/11/10
20713601BAG-6 is essential for selective elimination of defective proteasomal substrates.J Cell Biol, 2010 Aug 23;190(4);637-50, Minami R, Hayakawa A, ..., Yokosawa H, Kawahara H 0 2010/11/09
20676083A ribosome-associating factor chaperones tail-anchored membrane proteins.Nature, 2010 Aug 26;466(7310);1120-4, Mariappan M, Li X, ..., Keenan RJ, Hegde RS 0 2010/11/08
20723759ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.Cell, 2010 Aug 20;142(4);590-600, Radoshevich L, Murrow L, ..., Fung C, Debnath J 0 2010/10/04
20849418Autolytic activity of human calpain?7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction.FEBS J, 2010 Aug 24; [Epub ahead of print]Osako Y, Maemoto Y, ..., Shibata H, Maki M 0 2010/10/04
20723762Activation of specific apoptotic caspases with an engineered small-molecule-activated protease.Cell, 2010 Aug 20;142(4);637-46, Gray DC, Mahrus S, Wells JA 0 2010/09/23
20833710Contribution of K11-linked ubiquitination to MIR2-mediated MHC class I internalization.J Biol Chem, 2010 Sep 10; [Epub ahead of print]Goto E, Yamanaka Y, ..., Hirano H, Ishido S 0 2010/09/17
20725033Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.Nature, 2010 Aug 19;466(7309);941-6, Nakada S, Tai I, ..., Suda T, Durocher D 2 2010/08/25
20686710Calpain 8/nCL-2 and Calpain 9/nCL-4 Constitute an Active Protease Complex, G-Calpain, Involved in Gastric Mucosal Defense.PLoS Genet, 2010;6(7);e1001040, Hata S, Abe M, ..., Sakimura K, Sorimachi H 0 2010/08/10
20381137Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.Cell, 2010 Apr 16;141(2);290-303, Sancak Y, Bar-Peled L, ..., Nada S, Sabatini DM 4 2010/08/06
20604804p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria.Genes Cells, 2010 Aug;15(8);887-900, Okatsu K, Saisho K, ..., Tanaka K, Matsuda N 0 2010/08/03
20615880Autophagy-related protein (Atg) 8-family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway.J Biol Chem, 2010 Jul 8; [Epub ahead of print]Yamaguchi M, Noda NN, ..., Ohsumi Y, Inagaki F 0 2010/07/29
20659891Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by ATG19 and ATG34.J Biol Chem, 2010 Jul 21; [Epub ahead of print]Watanabe Y, Noda NN, ..., Ohsumi Y, Inagaki F 0 2010/07/29
20639194Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, ATG34.J Biol Chem, 2010 Jul 16; [Epub ahead of print]Suzuki K, Kondo C, Morimoto M, Ohsumi Y 1 2010/07/29
20639694Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.Autophagy, 2010 Aug 18;6(6); [Epub ahead of print]Itakura E, Mizushima N 2 2010/07/26
20620957Ecm29 fulfils quality control functions in proteasome assembly.Mol Cell, 2010 Jun 25;38(6);879-88, Lehmann A, Niewienda A, ..., Janek K, Enenkel C 0 2010/07/26
20592470Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.J Clin Invest, 2010 Jul 1; [Epub ahead of print]  0 2010/07/23
20417603Positive or negative roles of different cyclin-dependent kinase Pho85-cyclin complexes orchestrate induction of autophagy in Saccharomyces cerevisiae.Mol Cell, 2010 Apr 23;38(2);250-64, Yang Z, Geng J, ..., Wang K, Klionsky DJ 0 2010/06/23
20550938C. elegans screen identifies autophagy genes specific to multicellular organisms.Cell, 2010 Jun 11;141(6);1042-55, Tian Y, Li Z, ..., Yu L, Zhang H 0 2010/06/23
20478256Mitochondria supply membranes for autophagosome biogenesis during starvation.Cell, 2010 May 14;141(4);656-67, Hailey DW, Rambold AS, ..., Kim PK, Lippincott-Schwartz J 1 2010/06/23
20516148TRIM8 modulates STAT3 activity through negative regulation of PIAS3.J Cell Sci, 2010 Jun 1; [Epub ahead of print]Okumura F, Matsunaga Y, ..., Nakayama KI, Hatakeyama S 0 2010/06/14
20305637Molecular mechanism of multivesicular body biogenesis by ESCRT complexes.Nature, 2010 Apr 8;464(7290);864-9, Wollert T, Hurley JH 0 2010/06/04
20403326Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.Cell, 2010 Apr 16;141(2);315-30, Zeng W, Sun L, ..., Xu M, Chen ZJ 1 2010/06/02
20460380Skeletal muscle-specific calpain is an intracellular Na+-dependent protease.J Biol Chem, 2010 May 11; [Epub ahead of print]Ono Y, Ojima K, ..., Abe K, Sorimachi H 0 2010/05/31
20237562Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.Nature, 2010 Mar 18;464(7287);374-9, Lin HK, Chen Z, ..., Teruya-Feldstein J, Pandolfi PP 0 2010/05/30
20495530Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt.EMBO J, 2010 May 21; [Epub ahead of print]Mukai A, Yamamoto-Hino M, ..., Komada M, Goto S 0 2010/05/26
20228808Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.Nat Cell Biol, 2010 Apr;12(4);400-6, Pereg Y, Liu BY, ..., French DM, Dixit VM 0 2010/05/24
20427287Mammalian Tti1 and Tel2 are critical factors in mTOR complex assembly.J Biol Chem, 2010 Apr 28; [Epub ahead of print]Kaizuka T, Hara T, ..., Natsume T, Mizushima N 0 2010/05/10
20236927Crystal structure of yeast Rpn14, a chaperone of the 19S regulatory particle of the proteasome.J Biol Chem, 2010 Mar 16; [Epub ahead of print]Kim S, Saeki Y, ..., Mizushima T, Kato K 0 2010/05/10
20178748Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines.Cell, 2010 Feb 19;140(4);567-78, Bingol B, Wang CF, ..., Peng J, Sheng M 0 2010/05/06
20154084Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy.J Biol Chem, 2010 Apr 9;285(15);11476-88, Nair U, Cao Y, Xie Z, Klionsky DJ 0 2010/04/28
20404107PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.J Cell Biol, 2010 Apr 19;189(2);211-21, Matsuda N, Sato S, ..., Hattori N, Tanaka K 1 2010/04/22
20173742The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.Nat Cell Biol, 2010 Mar;12(3);213-23, Komatsu M, Kurokawa H, ..., Tanaka K, Yamamoto M 0 2010/04/14
20375281Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy.Proc Natl Acad Sci U S A, 2010 Apr 7; [Epub ahead of print]Lynch-Day MA, Bhandari D, ..., Ferro-Novick S, Klionsky DJ 0 2010/04/13
20026656IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.J Cell Biol, 2009 Dec 28;187(7);1083-99, Thompson LM, Aiken CT, ..., Marsh JL, Steffan JS 0 2010/04/05
20144757Methods in mammalian autophagy research.Cell, 2010 Feb 5;140(3);313-26, Mizushima N, Yoshimori T, Levine B 0 2010/04/03
20184884Autophagy.FEBS Lett, 2010 Apr 2;584(7);1279, Mizushima N 0 2010/04/03
19279007Roles of protein-disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in endoplasmic reticulum-associated degradation.J Biol Chem, 2009 May 1;284(18);11815-25, Sakoh-Nakatogawa M, Nishikawa S, Endo T 0 2010/03/15
20159449Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.Neuron, 2010 Feb 11;65(3);358-72, Kawabe H, Neeb A, ..., Rhee J, Brose N 0 2010/03/13
20159448E3 ligase Nedd4 promotes axon branching by downregulating PTEN.Neuron, 2010 Feb 11;65(3);341-57, Drinjakovic J, Jung H, ..., Dwivedy A, Holt CE 0 2010/03/13
20123978DYRK1A and Glycogen Synthase Kinase 3{beta}, a Dual-Kinase Mechanism Directing Proteasomal Degradation of CRY2 for Circadian Timekeeping.Mol Cell Biol, 2010 Apr;30(7);1757-68, Kurabayashi N, Hirota T, ..., Sanada K, Fukada Y 0 2010/03/12
20156962Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.J Cell Biol, 2010 Feb 15; [Epub ahead of print]Manjithaya R, Anjard C, Loomis WF, Subramani S 3 2010/03/04
20098416PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.Nat Cell Biol, 2010 Feb;12(2);119-31, Geisler S, Holmstrom KM, ..., Kahle PJ, Springer W 0 2010/03/02
20147545Reevaluation of Neurodegeneration in lurcher Mice: Constitutive Ion Fluxes Cause Cell Death with, Not by, Autophagy.J Neurosci, 2010 Feb 10;30(6);2177-87, Nishiyama J, Matsuda K, ..., Mizushima N, Yuzaki M 0 2010/02/15
20061387Proteasome assembly influences interaction with ubiquitinated proteins and shuttle-factors.J Biol Chem, 2010 Jan 8; [Epub ahead of print]Chandra A, Chen L, Liang H, Madura K 0 2010/02/13
20065092The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy.J Cell Biol, 2010 Jan 11;188(1);101-14, Yen WL, Shintani T, ..., Baba M, Klionsky DJ 1 2010/02/12
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