Proteolysis Forum
since 2009.04.08

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PubMedID Title Journal Author Re updated
21264221Possible Existence of Lysosome-Like Organella within Mitochondria and Its Role in Mitochondrial Quality Control.PLoS One, 2011;6(1);e16054, Miyamoto Y, Kitamura N, ..., Ichinose S, Arakawa H 0 2011/01/27
21220506p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.J Cell Biol, 2011 Jan 10;192(1);17-27, Itakura E, Mizushima N 0 2011/01/17
21098295From the Cover: Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.Proc Natl Acad Sci U S A, 2010 Dec 7;107(49);20992-7, Bohn S, Beck F, ..., Baumeister W, Nickell S 0 2010/12/09
20956561Endocytosis of the Aspartic Acid/Glutamic Acid Transporter Dip5 Is Triggered by Substrate-Dependent Recruitment of the Rsp5 Ubiquitin Ligase via the Arrestin-Like Protein Aly2.Mol Cell Biol, 2010 Dec;30(24);5598-607, Hatakeyama R, Kamiya M, Takahara T, Maeda T 0 2010/11/25
21045113Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris.J Cell Sci, 2010 Nov 2; [Epub ahead of print]Tamura N, Oku M, Sakai Y 0 2010/11/10
20713601BAG-6 is essential for selective elimination of defective proteasomal substrates.J Cell Biol, 2010 Aug 23;190(4);637-50, Minami R, Hayakawa A, ..., Yokosawa H, Kawahara H 0 2010/11/09
20676083A ribosome-associating factor chaperones tail-anchored membrane proteins.Nature, 2010 Aug 26;466(7310);1120-4, Mariappan M, Li X, ..., Keenan RJ, Hegde RS 0 2010/11/08
20723759ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.Cell, 2010 Aug 20;142(4);590-600, Radoshevich L, Murrow L, ..., Fung C, Debnath J 0 2010/10/04
20849418Autolytic activity of human calpain?7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction.FEBS J, 2010 Aug 24; [Epub ahead of print]Osako Y, Maemoto Y, ..., Shibata H, Maki M 0 2010/10/04
20723762Activation of specific apoptotic caspases with an engineered small-molecule-activated protease.Cell, 2010 Aug 20;142(4);637-46, Gray DC, Mahrus S, Wells JA 0 2010/09/23
20833710Contribution of K11-linked ubiquitination to MIR2-mediated MHC class I internalization.J Biol Chem, 2010 Sep 10; [Epub ahead of print]Goto E, Yamanaka Y, ..., Hirano H, Ishido S 0 2010/09/17
20725033Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.Nature, 2010 Aug 19;466(7309);941-6, Nakada S, Tai I, ..., Suda T, Durocher D 2 2010/08/25
20686710Calpain 8/nCL-2 and Calpain 9/nCL-4 Constitute an Active Protease Complex, G-Calpain, Involved in Gastric Mucosal Defense.PLoS Genet, 2010;6(7);e1001040, Hata S, Abe M, ..., Sakimura K, Sorimachi H 0 2010/08/10
20381137Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.Cell, 2010 Apr 16;141(2);290-303, Sancak Y, Bar-Peled L, ..., Nada S, Sabatini DM 4 2010/08/06
20604804p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria.Genes Cells, 2010 Aug;15(8);887-900, Okatsu K, Saisho K, ..., Tanaka K, Matsuda N 0 2010/08/03
20615880Autophagy-related protein (Atg) 8-family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway.J Biol Chem, 2010 Jul 8; [Epub ahead of print]Yamaguchi M, Noda NN, ..., Ohsumi Y, Inagaki F 0 2010/07/29
20659891Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by ATG19 and ATG34.J Biol Chem, 2010 Jul 21; [Epub ahead of print]Watanabe Y, Noda NN, ..., Ohsumi Y, Inagaki F 0 2010/07/29
20639194Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, ATG34.J Biol Chem, 2010 Jul 16; [Epub ahead of print]Suzuki K, Kondo C, Morimoto M, Ohsumi Y 1 2010/07/29
20639694Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.Autophagy, 2010 Aug 18;6(6); [Epub ahead of print]Itakura E, Mizushima N 2 2010/07/26
20620957Ecm29 fulfils quality control functions in proteasome assembly.Mol Cell, 2010 Jun 25;38(6);879-88, Lehmann A, Niewienda A, ..., Janek K, Enenkel C 0 2010/07/26
20592470Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.J Clin Invest, 2010 Jul 1; [Epub ahead of print]  0 2010/07/23
20417603Positive or negative roles of different cyclin-dependent kinase Pho85-cyclin complexes orchestrate induction of autophagy in Saccharomyces cerevisiae.Mol Cell, 2010 Apr 23;38(2);250-64, Yang Z, Geng J, ..., Wang K, Klionsky DJ 0 2010/06/23
20550938C. elegans screen identifies autophagy genes specific to multicellular organisms.Cell, 2010 Jun 11;141(6);1042-55, Tian Y, Li Z, ..., Yu L, Zhang H 0 2010/06/23
20478256Mitochondria supply membranes for autophagosome biogenesis during starvation.Cell, 2010 May 14;141(4);656-67, Hailey DW, Rambold AS, ..., Kim PK, Lippincott-Schwartz J 1 2010/06/23
20516148TRIM8 modulates STAT3 activity through negative regulation of PIAS3.J Cell Sci, 2010 Jun 1; [Epub ahead of print]Okumura F, Matsunaga Y, ..., Nakayama KI, Hatakeyama S 0 2010/06/14
20305637Molecular mechanism of multivesicular body biogenesis by ESCRT complexes.Nature, 2010 Apr 8;464(7290);864-9, Wollert T, Hurley JH 0 2010/06/04
20403326Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.Cell, 2010 Apr 16;141(2);315-30, Zeng W, Sun L, ..., Xu M, Chen ZJ 1 2010/06/02
20460380Skeletal muscle-specific calpain is an intracellular Na+-dependent protease.J Biol Chem, 2010 May 11; [Epub ahead of print]Ono Y, Ojima K, ..., Abe K, Sorimachi H 0 2010/05/31
20237562Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.Nature, 2010 Mar 18;464(7287);374-9, Lin HK, Chen Z, ..., Teruya-Feldstein J, Pandolfi PP 0 2010/05/30
20495530Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt.EMBO J, 2010 May 21; [Epub ahead of print]Mukai A, Yamamoto-Hino M, ..., Komada M, Goto S 0 2010/05/26
20228808Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.Nat Cell Biol, 2010 Apr;12(4);400-6, Pereg Y, Liu BY, ..., French DM, Dixit VM 0 2010/05/24
20427287Mammalian Tti1 and Tel2 are critical factors in mTOR complex assembly.J Biol Chem, 2010 Apr 28; [Epub ahead of print]Kaizuka T, Hara T, ..., Natsume T, Mizushima N 0 2010/05/10
20236927Crystal structure of yeast Rpn14, a chaperone of the 19S regulatory particle of the proteasome.J Biol Chem, 2010 Mar 16; [Epub ahead of print]Kim S, Saeki Y, ..., Mizushima T, Kato K 0 2010/05/10
20178748Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines.Cell, 2010 Feb 19;140(4);567-78, Bingol B, Wang CF, ..., Peng J, Sheng M 0 2010/05/06
20154084Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy.J Biol Chem, 2010 Apr 9;285(15);11476-88, Nair U, Cao Y, Xie Z, Klionsky DJ 0 2010/04/28
20404107PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.J Cell Biol, 2010 Apr 19;189(2);211-21, Matsuda N, Sato S, ..., Hattori N, Tanaka K 1 2010/04/22
20173742The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.Nat Cell Biol, 2010 Mar;12(3);213-23, Komatsu M, Kurokawa H, ..., Tanaka K, Yamamoto M 0 2010/04/14
20375281Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy.Proc Natl Acad Sci U S A, 2010 Apr 7; [Epub ahead of print]Lynch-Day MA, Bhandari D, ..., Ferro-Novick S, Klionsky DJ 0 2010/04/13
20026656IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.J Cell Biol, 2009 Dec 28;187(7);1083-99, Thompson LM, Aiken CT, ..., Marsh JL, Steffan JS 0 2010/04/05
20144757Methods in mammalian autophagy research.Cell, 2010 Feb 5;140(3);313-26, Mizushima N, Yoshimori T, Levine B 0 2010/04/03
20184884Autophagy.FEBS Lett, 2010 Apr 2;584(7);1279, Mizushima N 0 2010/04/03
19279007Roles of protein-disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in endoplasmic reticulum-associated degradation.J Biol Chem, 2009 May 1;284(18);11815-25, Sakoh-Nakatogawa M, Nishikawa S, Endo T 0 2010/03/15
20159449Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.Neuron, 2010 Feb 11;65(3);358-72, Kawabe H, Neeb A, ..., Rhee J, Brose N 0 2010/03/13
20159448E3 ligase Nedd4 promotes axon branching by downregulating PTEN.Neuron, 2010 Feb 11;65(3);341-57, Drinjakovic J, Jung H, ..., Dwivedy A, Holt CE 0 2010/03/13
20123978DYRK1A and Glycogen Synthase Kinase 3{beta}, a Dual-Kinase Mechanism Directing Proteasomal Degradation of CRY2 for Circadian Timekeeping.Mol Cell Biol, 2010 Apr;30(7);1757-68, Kurabayashi N, Hirota T, ..., Sanada K, Fukada Y 0 2010/03/12
20156962Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.J Cell Biol, 2010 Feb 15; [Epub ahead of print]Manjithaya R, Anjard C, Loomis WF, Subramani S 3 2010/03/04
20098416PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.Nat Cell Biol, 2010 Feb;12(2);119-31, Geisler S, Holmstrom KM, ..., Kahle PJ, Springer W 0 2010/03/02
20147545Reevaluation of Neurodegeneration in lurcher Mice: Constitutive Ion Fluxes Cause Cell Death with, Not by, Autophagy.J Neurosci, 2010 Feb 10;30(6);2177-87, Nishiyama J, Matsuda K, ..., Mizushima N, Yuzaki M 0 2010/02/15
20061387Proteasome assembly influences interaction with ubiquitinated proteins and shuttle-factors.J Biol Chem, 2010 Jan 8; [Epub ahead of print]Chandra A, Chen L, Liang H, Madura K 0 2010/02/13
20065092The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy.J Cell Biol, 2010 Jan 11;188(1);101-14, Yen WL, Shintani T, ..., Baba M, Klionsky DJ 1 2010/02/12
20139071Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing.J Biol Chem, 2010 Feb 4; [Epub ahead of print]Mimura S, Yamaguchi T, ..., Obuse C, Kamura T 0 2010/02/12
19956254Detection of sequential polyubiquitylation on a millisecond timescale.Nature, 2009 Dec 3;462(7273);615-9, Pierce NW, Kleiger G, Shan SO, Deshaies RJ 0 2010/02/11
20010695Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1.EMBO J, 2010 Feb 3;29(3);606-18, Chang NC, Nguyen M, Germain M, Shore GC 0 2010/02/10
20045355Thymoproteasome Shapes Immunocompetent Repertoire of CD8(+) T Cells.Immunity, 2009 Dec 30; [Epub ahead of print]Nitta T, Murata S, ..., Tanaka K, Takahama Y 0 2010/02/09
20023420Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells.Cell Cycle, 2010 Jan 15;9(2);377-83, Shen S, Kepp O, ..., Pierron G, Kroemer G 0 2010/02/08
19793721Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.Hum Mol Genet, 2009 Dec 15;18(24);4868-78, Ferguson CJ, Lenk GM, Meisler MH 0 2010/02/08
20093466The genetic landscape of a cell.Science, 2010 Jan 22;327(5964);425-31, Costanzo M, Baryshnikova A, ..., Andrews BJ, Boone C 0 2010/02/04
20018847A novel type of E3-ligase for the Ufm1-conjugation system.J Biol Chem, 2009 Dec 14; [Epub ahead of print]Tatsumi K, Sou YS, ..., Tanaka K, Komatsu M 0 2009/12/21
19749745Listeria monocytogenes ActA-mediated escape from autophagic recognition.Nat Cell Biol, 2009 Oct;11(10);1233-40, Yoshikawa Y, Ogawa M, ..., Chakraborty T, Sasakawa C 0 2009/11/25
19773385Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis.Plant Cell, 2009 Sep;21(9);2914-27, Yoshimoto K, Jikumaru Y, ..., Ohsumi Y, Shirasu K 0 2009/11/22
19910927SCF(Dia2) regulates DNA replication forks during S-phase in budding yeast.EMBO J, 2009 Nov 12; [Epub ahead of print]Mimura S, Komata M, ..., Shirahige K, Kamura T 0 2009/11/18
19671920Specific iron chelators determine the route of ferritin degradation.Blood, 2009 Aug 11; [Epub ahead of print]De Domenico I, Ward DM, Kaplan J 0 2009/11/15
19783656Differencial involvement of ATG16L1 in Crohn's disease and canonical autophagy: analysis of the organization of the ATG16L1 complex in fibroblasts.J Biol Chem, 2009 Sep 25; [Epub ahead of print]Fujita N, Saitoh T, ..., Noda T, Yoshimori T 0 2009/11/14
19889643The dimeric coiled-coil structure of Saccharomyces cerevisiae ATG16 and its functional significance in autophagy.J Biol Chem, 2009 Nov 4; [Epub ahead of print]Fujioka Y, Noda NN, ..., Ohsumi Y, Inagaki F 1 2009/11/14
19778961Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation.Microbiology, 2009 Sep 24; [Epub ahead of print]Mukaiyama H, Kajiwara S, ..., Nakamura T, Takegawa K 1 2009/11/10
19549169Lag-phase autophagy in the methylotrophic yeast Pichia pastoris.Genes Cells, 2009 Jul;14(7);861-70, Yamashita S, Yurimoto H, ..., Oku M, Sakai Y 0 2009/11/10
19793921A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy.Mol Biol Cell, 2009 Sep 30; [Epub ahead of print]Kanki T, Wang K, ..., Yen WL, Klionsky DJ 0 2009/11/09
19550147Autophagic degradation of nuclear components in mammalian cells.Autophagy, 2009 Aug;5(6);795-804, Park YE, Hayashi YK, ..., Nonaka I, Nishino I 0 2009/11/09
19625776Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles.Autophagy, 2009 Oct;5(7);937-45, Tanida I, Fukasawa M, ..., Wakita T, Hanada K 0 2009/11/09
19755117Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae.Biochem Biophys Res Commun, 2009 Sep 13; [Epub ahead of print]Kabeya Y, Noda NN, ..., Inagaki F, Ohsumi Y 1 2009/09/24
19763088A longevity protein, Lag2, interacts with SCF complex and regulates SCF function.EMBO J, 2009 Sep 17; [Epub ahead of print]Liu Y, Mimura S, Kishi T, Kamura T 0 2009/09/22
19164769A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development.Proc Natl Acad Sci U S A, 2009 Feb 3;106(5);1554-9, Russo I, Oksman A, Vaupel B, Goldberg DE 0 2009/08/18
19597335Atg101, a novel mammalian autophagy protein interacting with Atg13.Autophagy, 2009 Oct 18;5(7); [Epub ahead of print]Hosokawa N, Sasaki T, ..., Hara T, Mizushima N 0 2009/07/30
19619494Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy.Dev Cell, 2009 Jul;17(1);87-97, Okamoto K, Kondo-Okamoto N, Ohsumi Y 0 2009/07/22
19458266Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy.Proc Natl Acad Sci U S A, 2009 Jun 2;106(22);8923-8, Zhou X, Ikenoue T, ..., Inoki K, Guan KL 0 2009/07/02
19450522Autophagic components contribute to hypersensitive cell death in Arabidopsis.Cell, 2009 May 15;137(4);773-83, Hofius D, Schultz-Larsen T, ..., Mundy J, Petersen M 0 2009/06/19
19229298Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3.EMBO J, 2009 Apr 8;28(7);889-901, Gamerdinger M, Hajieva P, ..., Hartl FU, Behl C 0 2009/06/15
18724939Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.Cell, 2008 Aug 22;134(4);668-78, Newton K, Matsumoto ML, ..., Kelley RF, Dixit VM 1 2009/06/15
19490896Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.Cell, 2009 May 29;137(5);914-25, Kaneko T, Hamazaki J, ..., Tanaka K, Murata S 0 2009/06/07
19339495Activation of antibacterial autophagy by NADPH oxidases.Proc Natl Acad Sci U S A, 2009 Apr 14;106(15);6226-31, Huang J, Canadien V, ..., Grinstein S, Brumell JH 0 2009/05/28
17525341RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.Science, 2007 May 25;316(5828);1198-202, Sobhian B, Shao G, ..., Livingston DM, Greenberg RA 5 2009/05/22
19446323Multiple Proteasome-Interacting Proteins Assist the Assembly of the Yeast 19S Regulatory Particle.Cell, 2009 May 13; [Epub ahead of print]Saeki Y, Toh-E A, ..., Kawamura H, Tanaka K 0 2009/05/20
19410548An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.Cell, 2009 May 1;137(3);549-59, Kimura Y, Yashiroda H, ..., Kakizuka A, Tanaka K 0 2009/05/15
19270693Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.Nat Cell Biol, 2009 Apr;11(4);468-76, Zhong Y, Wang QJ, ..., Heintz N, Yue Z 0 2009/05/15
19339967Autophagy regulates lipid metabolism.Nature, 2009 Apr 30;458(7242);1131-5, Singh R, Kaushik S, ..., Cuervo AM, Czaja MJ 0 2009/05/12
19345187Acetylation targets mutant huntingtin to autophagosomes for degradation.Cell, 2009 Apr 3;137(1);60-72, Jeong H, Then F, ..., Yamamoto A, Krainc D 0 2009/05/11
19379691VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification.Cell, 2009 Apr 17;137(2);235-46, Ramachandran N, Munteanu I, ..., Ackerley CA, Minassian BA 1 2009/05/11
19363139Atg26-Mediated Pexophagy Is Required for Host Invasion by the Plant Pathogenic Fungus Colletotrichum orbiculare.Plant Cell, 2009 Apr 10; [Epub ahead of print]Asakura M, Ninomiya S, ..., Sakai Y, Takano Y 0 2009/04/20
19322194The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.EMBO J, 2009 Mar 26; [Epub ahead of print]Satoo K, Noda NN, ..., Ohsumi Y, Inagaki F 0 2009/04/01
19240038Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration.J Biol Chem, 2009 Feb 24; [Epub ahead of print]Rudinskiy N, Grishchuk Y, ..., Clarke PG, Luthi-Carter R 0 2009/03/31
19270696Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.Nat Cell Biol, 2009 Mar 8; [Epub ahead of print]Matsunaga K, Saitoh T, ..., Noda T, Yoshimori T 0 2009/03/25
19203585Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy.Cell, 2009 Feb 6;136(3);521-534, Nicklin P, Bergman P, ..., Finan PM, Murphy LO 1 2009/03/23
19211835Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy.Mol Biol Cell, 2009 Feb 11; [Epub ahead of print]Hosokawa N, Hara T, ..., Oshiro N, Mizushima N 0 2009/03/06
19250912Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.Mol Cell, 2009 Feb 27;33(4);517-27, Korolchuk VI, Mansilla A, Menzies FM, Rubinsztein DC 0 2009/03/04
19250911A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates.Mol Cell, 2009 Feb 27;33(4);505-16, Kirkin V, Lamark T, ..., Dikic I, Johansen T 0 2009/03/04
19203578The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.Cell, 2009 Feb 6;136(3);420-34, Stewart GS, Panier S, ..., Taylor AM, Durocher D 0 2009/02/27
19236009ATG Systems from the Protein Structural Point of View.Chem Rev, 2009 Feb 23; [Epub ahead of print]Noda NN, Ohsumi Y, Inagaki F 0 2009/02/26
19150980An ATP-competitive mTOR inhibitor reveals rapamycin-insensitive functions of mTORC1.J Biol Chem, 2009 Jan 15; [Epub ahead of print]Thoreen CC, Kang SA, ..., Sabatini DM, Gray NS 2 2009/02/12
19136968Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.Nat Cell Biol, 2009 Feb;11(2);123-32, Tokunaga F, Sakata S, ..., Tanaka K, Iwai K 0 2009/02/09
19167332SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans.Cell, 2009 Jan 23;136(2);308-21, Zhang Y, Yan L, ..., Miao L, Zhang H 0 2009/01/28
18722006Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini.Cell, 2008 Sep 5;134(5);866-76, Mahrus S, Trinidad JC, ..., Burlingame AL, Wells JA 0 2009/01/14
19117993BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.Cancer Res, 2009 Jan 1;69(1);111-9, Nishikawa H, Wu W, ..., Fukuda M, Ohta T 0 2009/01/08
19088090Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of {beta}-catenin/Arm and stimulation of target gene expression.Development, 2009 Jan;136(2);241-51, Lee W, Swarup S, ..., Ishitani T, Verheyen EM 0 2009/01/07
19119233Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy.Science, 2009 Jan 2;323(5910);124-7, Yang Q, She H, ..., Shacka JJ, Mao Z 0 2009/01/07
18832610Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.Science, 2008 Nov 14;322(5904);1104-7, Pearce MJ, Mintseris J, ..., Gygi SP, Darwin KH 0 2008/12/15
19050071Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase.Proc Natl Acad Sci U S A, 2008 Dec 2; [Epub ahead of print]Sun Q, Fan W, ..., Chen S, Zhong Q 0 2008/12/05
19029340Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.J Cell Biol, 2008 Nov 24; [Epub ahead of print]Narendra D, Tanaka A, Suen DF, Youle RJ 3 2008/12/04
19021777Structural basis of target recognition by Atg8/LC3 during selective autophagy.Genes Cells, 2008 Oct 22; [Epub ahead of print]Noda NN, Kumeta H, ..., Ohsumi Y, Inagaki F 0 2008/12/03
18997778Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.Nat Struct Mol Biol, 2008 Nov 9; [Epub ahead of print]Singer AU, Rohde JR, ..., Parsot C, Savchenko A 0 2008/12/03
19020622Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.Nature, 2008 Nov 20;456(7220);404-408, Moldoveanu T, Gehring K, Green DR 1 2008/11/30
19020623Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin.Nature, 2008 Nov 20;456(7220);409-12, Hanna RA, Campbell RL, Davies PL 0 2008/11/29
18757741Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.Proc Natl Acad Sci U S A, 2008 Sep 9;105(36);13568-73, Shibata T, Ohta T, ..., Yamamoto M, Hirohashi S 0 2008/11/24
18829864Self-Interaction Is Critical for Atg9 Transport and Function at the Phagophore Assembly Site during Autophagy.Mol Biol Cell, 2008 Oct 1; [Epub ahead of print]He C, Baba M, Cao Y, Klionsky DJ 1 2008/11/19
18948269RalA functions as an indispensable signal mediator for nutrient sensing system.J Biol Chem, 2008 Oct 23; [Epub ahead of print]Maehama T, Tanaka M, ..., Kanaho Y, Hanada K 0 2008/11/18
18716223Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli.J Neurosci, 2008 Aug 20;28(34);8644-54, Purro SA, Ciani L, ..., Siomou E, Salinas PC 0 2008/11/14
18812319Isolation of hyperactive mutants of mammalian target of rapamycin.J Biol Chem, 2008 Sep 23; [Epub ahead of print]Ohne Y, Takahara T, ..., Mizushima N, Maeda T 0 2008/11/10
18948957Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.Nature, 2008 Oct 23;455(7216);1134-7, Kim HJ, Oh SA, ..., Twell D, Nam HG 0 2008/11/05
18936157Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domain using an Atg13-independent mechanism.Mol Cell Biol, 2008 Oct 20; [Epub ahead of print]Chan EY, Longatti A, McKnight NC, Tooze SA 0 2008/11/05
18353967Ubiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion.Mol Biol Cell, 2008 Jun;19(6);2457-64, Cohen MM, Leboucher GP, ..., Glickman MH, Weissman AM 0 2008/10/31
18940611Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism.Structure, 2008 Oct;16(10);1562-73, Suzuki H, Kawasaki M, ..., Wakatsuki S, Maki M 0 2008/10/27
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17687326Global changes to the ubiquitin system in Huntington's disease.Nature, 2007 Aug 9;448(7154);704-8, Bennett EJ, Shaler TA, ..., Schulman H, Kopito RR 0 2007/09/04
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