Proteolysis Forum
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PubMedID Title Journal Author Re updated
20139071Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing.J Biol Chem, 2010 Feb 4; [Epub ahead of print]Mimura S, Yamaguchi T, ..., Obuse C, Kamura T 0 2010/02/12
19956254Detection of sequential polyubiquitylation on a millisecond timescale.Nature, 2009 Dec 3;462(7273);615-9, Pierce NW, Kleiger G, Shan SO, Deshaies RJ 0 2010/02/11
20010695Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1.EMBO J, 2010 Feb 3;29(3);606-18, Chang NC, Nguyen M, Germain M, Shore GC 0 2010/02/10
20045355Thymoproteasome Shapes Immunocompetent Repertoire of CD8(+) T Cells.Immunity, 2009 Dec 30; [Epub ahead of print]Nitta T, Murata S, ..., Tanaka K, Takahama Y 0 2010/02/09
20023420Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells.Cell Cycle, 2010 Jan 15;9(2);377-83, Shen S, Kepp O, ..., Pierron G, Kroemer G 0 2010/02/08
19793721Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.Hum Mol Genet, 2009 Dec 15;18(24);4868-78, Ferguson CJ, Lenk GM, Meisler MH 0 2010/02/08
20093466The genetic landscape of a cell.Science, 2010 Jan 22;327(5964);425-31, Costanzo M, Baryshnikova A, ..., Andrews BJ, Boone C 0 2010/02/04
20018847A novel type of E3-ligase for the Ufm1-conjugation system.J Biol Chem, 2009 Dec 14; [Epub ahead of print]Tatsumi K, Sou YS, ..., Tanaka K, Komatsu M 0 2009/12/21
19749745Listeria monocytogenes ActA-mediated escape from autophagic recognition.Nat Cell Biol, 2009 Oct;11(10);1233-40, Yoshikawa Y, Ogawa M, ..., Chakraborty T, Sasakawa C 0 2009/11/25
19773385Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis.Plant Cell, 2009 Sep;21(9);2914-27, Yoshimoto K, Jikumaru Y, ..., Ohsumi Y, Shirasu K 0 2009/11/22
19910927SCF(Dia2) regulates DNA replication forks during S-phase in budding yeast.EMBO J, 2009 Nov 12; [Epub ahead of print]Mimura S, Komata M, ..., Shirahige K, Kamura T 0 2009/11/18
19671920Specific iron chelators determine the route of ferritin degradation.Blood, 2009 Aug 11; [Epub ahead of print]De Domenico I, Ward DM, Kaplan J 0 2009/11/15
19783656Differencial involvement of ATG16L1 in Crohn's disease and canonical autophagy: analysis of the organization of the ATG16L1 complex in fibroblasts.J Biol Chem, 2009 Sep 25; [Epub ahead of print]Fujita N, Saitoh T, ..., Noda T, Yoshimori T 0 2009/11/14
19889643The dimeric coiled-coil structure of Saccharomyces cerevisiae ATG16 and its functional significance in autophagy.J Biol Chem, 2009 Nov 4; [Epub ahead of print]Fujioka Y, Noda NN, ..., Ohsumi Y, Inagaki F 1 2009/11/14
19778961Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation.Microbiology, 2009 Sep 24; [Epub ahead of print]Mukaiyama H, Kajiwara S, ..., Nakamura T, Takegawa K 1 2009/11/10
19549169Lag-phase autophagy in the methylotrophic yeast Pichia pastoris.Genes Cells, 2009 Jul;14(7);861-70, Yamashita S, Yurimoto H, ..., Oku M, Sakai Y 0 2009/11/10
19793921A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy.Mol Biol Cell, 2009 Sep 30; [Epub ahead of print]Kanki T, Wang K, ..., Yen WL, Klionsky DJ 0 2009/11/09
19550147Autophagic degradation of nuclear components in mammalian cells.Autophagy, 2009 Aug;5(6);795-804, Park YE, Hayashi YK, ..., Nonaka I, Nishino I 0 2009/11/09
19625776Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles.Autophagy, 2009 Oct;5(7);937-45, Tanida I, Fukasawa M, ..., Wakita T, Hanada K 0 2009/11/09
19755117Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae.Biochem Biophys Res Commun, 2009 Sep 13; [Epub ahead of print]Kabeya Y, Noda NN, ..., Inagaki F, Ohsumi Y 1 2009/09/24
19763088A longevity protein, Lag2, interacts with SCF complex and regulates SCF function.EMBO J, 2009 Sep 17; [Epub ahead of print]Liu Y, Mimura S, Kishi T, Kamura T 0 2009/09/22
19164769A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development.Proc Natl Acad Sci U S A, 2009 Feb 3;106(5);1554-9, Russo I, Oksman A, Vaupel B, Goldberg DE 0 2009/08/18
19597335Atg101, a novel mammalian autophagy protein interacting with Atg13.Autophagy, 2009 Oct 18;5(7); [Epub ahead of print]Hosokawa N, Sasaki T, ..., Hara T, Mizushima N 0 2009/07/30
19619494Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy.Dev Cell, 2009 Jul;17(1);87-97, Okamoto K, Kondo-Okamoto N, Ohsumi Y 0 2009/07/22
19458266Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy.Proc Natl Acad Sci U S A, 2009 Jun 2;106(22);8923-8, Zhou X, Ikenoue T, ..., Inoki K, Guan KL 0 2009/07/02
19450522Autophagic components contribute to hypersensitive cell death in Arabidopsis.Cell, 2009 May 15;137(4);773-83, Hofius D, Schultz-Larsen T, ..., Mundy J, Petersen M 0 2009/06/19
19229298Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3.EMBO J, 2009 Apr 8;28(7);889-901, Gamerdinger M, Hajieva P, ..., Hartl FU, Behl C 0 2009/06/15
18724939Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.Cell, 2008 Aug 22;134(4);668-78, Newton K, Matsumoto ML, ..., Kelley RF, Dixit VM 1 2009/06/15
19490896Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.Cell, 2009 May 29;137(5);914-25, Kaneko T, Hamazaki J, ..., Tanaka K, Murata S 0 2009/06/07
19339495Activation of antibacterial autophagy by NADPH oxidases.Proc Natl Acad Sci U S A, 2009 Apr 14;106(15);6226-31, Huang J, Canadien V, ..., Grinstein S, Brumell JH 0 2009/05/28
17525341RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.Science, 2007 May 25;316(5828);1198-202, Sobhian B, Shao G, ..., Livingston DM, Greenberg RA 5 2009/05/22
19446323Multiple Proteasome-Interacting Proteins Assist the Assembly of the Yeast 19S Regulatory Particle.Cell, 2009 May 13; [Epub ahead of print]Saeki Y, Toh-E A, ..., Kawamura H, Tanaka K 0 2009/05/20
19410548An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.Cell, 2009 May 1;137(3);549-59, Kimura Y, Yashiroda H, ..., Kakizuka A, Tanaka K 0 2009/05/15
19270693Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.Nat Cell Biol, 2009 Apr;11(4);468-76, Zhong Y, Wang QJ, ..., Heintz N, Yue Z 0 2009/05/15
19339967Autophagy regulates lipid metabolism.Nature, 2009 Apr 30;458(7242);1131-5, Singh R, Kaushik S, ..., Cuervo AM, Czaja MJ 0 2009/05/12
19345187Acetylation targets mutant huntingtin to autophagosomes for degradation.Cell, 2009 Apr 3;137(1);60-72, Jeong H, Then F, ..., Yamamoto A, Krainc D 0 2009/05/11
19379691VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification.Cell, 2009 Apr 17;137(2);235-46, Ramachandran N, Munteanu I, ..., Ackerley CA, Minassian BA 1 2009/05/11
19363139Atg26-Mediated Pexophagy Is Required for Host Invasion by the Plant Pathogenic Fungus Colletotrichum orbiculare.Plant Cell, 2009 Apr 10; [Epub ahead of print]Asakura M, Ninomiya S, ..., Sakai Y, Takano Y 0 2009/04/20
19322194The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.EMBO J, 2009 Mar 26; [Epub ahead of print]Satoo K, Noda NN, ..., Ohsumi Y, Inagaki F 0 2009/04/01
19240038Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration.J Biol Chem, 2009 Feb 24; [Epub ahead of print]Rudinskiy N, Grishchuk Y, ..., Clarke PG, Luthi-Carter R 0 2009/03/31
19270696Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.Nat Cell Biol, 2009 Mar 8; [Epub ahead of print]Matsunaga K, Saitoh T, ..., Noda T, Yoshimori T 0 2009/03/25
19203585Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy.Cell, 2009 Feb 6;136(3);521-534, Nicklin P, Bergman P, ..., Finan PM, Murphy LO 1 2009/03/23
19211835Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy.Mol Biol Cell, 2009 Feb 11; [Epub ahead of print]Hosokawa N, Hara T, ..., Oshiro N, Mizushima N 0 2009/03/06
19250912Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.Mol Cell, 2009 Feb 27;33(4);517-27, Korolchuk VI, Mansilla A, Menzies FM, Rubinsztein DC 0 2009/03/04
19250911A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates.Mol Cell, 2009 Feb 27;33(4);505-16, Kirkin V, Lamark T, ..., Dikic I, Johansen T 0 2009/03/04
19203578The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.Cell, 2009 Feb 6;136(3);420-34, Stewart GS, Panier S, ..., Taylor AM, Durocher D 0 2009/02/27
19236009ATG Systems from the Protein Structural Point of View.Chem Rev, 2009 Feb 23; [Epub ahead of print]Noda NN, Ohsumi Y, Inagaki F 0 2009/02/26
19150980An ATP-competitive mTOR inhibitor reveals rapamycin-insensitive functions of mTORC1.J Biol Chem, 2009 Jan 15; [Epub ahead of print]Thoreen CC, Kang SA, ..., Sabatini DM, Gray NS 2 2009/02/12
19136968Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.Nat Cell Biol, 2009 Feb;11(2);123-32, Tokunaga F, Sakata S, ..., Tanaka K, Iwai K 0 2009/02/09
19167332SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans.Cell, 2009 Jan 23;136(2);308-21, Zhang Y, Yan L, ..., Miao L, Zhang H 0 2009/01/28
18722006Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini.Cell, 2008 Sep 5;134(5);866-76, Mahrus S, Trinidad JC, ..., Burlingame AL, Wells JA 0 2009/01/14
19117993BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.Cancer Res, 2009 Jan 1;69(1);111-9, Nishikawa H, Wu W, ..., Fukuda M, Ohta T 0 2009/01/08
19088090Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of {beta}-catenin/Arm and stimulation of target gene expression.Development, 2009 Jan;136(2);241-51, Lee W, Swarup S, ..., Ishitani T, Verheyen EM 0 2009/01/07
19119233Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy.Science, 2009 Jan 2;323(5910);124-7, Yang Q, She H, ..., Shacka JJ, Mao Z 0 2009/01/07
18832610Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.Science, 2008 Nov 14;322(5904);1104-7, Pearce MJ, Mintseris J, ..., Gygi SP, Darwin KH 0 2008/12/15
19050071Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase.Proc Natl Acad Sci U S A, 2008 Dec 2; [Epub ahead of print]Sun Q, Fan W, ..., Chen S, Zhong Q 0 2008/12/05
19029340Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.J Cell Biol, 2008 Nov 24; [Epub ahead of print]Narendra D, Tanaka A, Suen DF, Youle RJ 3 2008/12/04
19021777Structural basis of target recognition by Atg8/LC3 during selective autophagy.Genes Cells, 2008 Oct 22; [Epub ahead of print]Noda NN, Kumeta H, ..., Ohsumi Y, Inagaki F 0 2008/12/03
18997778Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.Nat Struct Mol Biol, 2008 Nov 9; [Epub ahead of print]Singer AU, Rohde JR, ..., Parsot C, Savchenko A 0 2008/12/03
19020622Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.Nature, 2008 Nov 20;456(7220);404-408, Moldoveanu T, Gehring K, Green DR 1 2008/11/30
19020623Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin.Nature, 2008 Nov 20;456(7220);409-12, Hanna RA, Campbell RL, Davies PL 0 2008/11/29
18757741Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.Proc Natl Acad Sci U S A, 2008 Sep 9;105(36);13568-73, Shibata T, Ohta T, ..., Yamamoto M, Hirohashi S 0 2008/11/24
18829864Self-Interaction Is Critical for Atg9 Transport and Function at the Phagophore Assembly Site during Autophagy.Mol Biol Cell, 2008 Oct 1; [Epub ahead of print]He C, Baba M, Cao Y, Klionsky DJ 1 2008/11/19
18948269RalA functions as an indispensable signal mediator for nutrient sensing system.J Biol Chem, 2008 Oct 23; [Epub ahead of print]Maehama T, Tanaka M, ..., Kanaho Y, Hanada K 0 2008/11/18
18716223Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli.J Neurosci, 2008 Aug 20;28(34);8644-54, Purro SA, Ciani L, ..., Siomou E, Salinas PC 0 2008/11/14
18812319Isolation of hyperactive mutants of mammalian target of rapamycin.J Biol Chem, 2008 Sep 23; [Epub ahead of print]Ohne Y, Takahara T, ..., Mizushima N, Maeda T 0 2008/11/10
18948957Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.Nature, 2008 Oct 23;455(7216);1134-7, Kim HJ, Oh SA, ..., Twell D, Nam HG 0 2008/11/05
18936157Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domain using an Atg13-independent mechanism.Mol Cell Biol, 2008 Oct 20; [Epub ahead of print]Chan EY, Longatti A, McKnight NC, Tooze SA 0 2008/11/05
18353967Ubiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion.Mol Biol Cell, 2008 Jun;19(6);2457-64, Cohen MM, Leboucher GP, ..., Glickman MH, Weissman AM 0 2008/10/31
18940611Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism.Structure, 2008 Oct;16(10);1562-73, Suzuki H, Kawasaki M, ..., Wakatsuki S, Maki M 0 2008/10/27
18843052Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG.Mol Biol Cell, 2008 Oct 8; [Epub ahead of print]Itakura E, Kishi C, Inoue K, Mizushima N 4 2008/10/23
0;  1 2008/10/21
18849965Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.Nature, 2008 Oct 5; [Epub ahead of print]Saitoh T, Fujita N, ..., Yoshimori T, Akira S 0 2008/10/20
18818209Mitophagy in yeast occurs through a selective mechanism.J Biol Chem, 2008 Sep 25; [Epub ahead of print]Kanki T, Klionsky DJ 0 2008/10/20
18662542Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes.Cell, 2008 Jul 25;134(2);268-78, Lee I, Schindelin H 0 2008/10/14
18756251Misfolded proteins partition between two distinct quality control compartments.Nature, 2008 Aug 28;454(7208);1088-95, Kaganovich D, Kopito R, Frydman J 0 2008/10/02
18818692Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity.EMBO J, 2008 Sep 25; [Epub ahead of print]Maestre C, Delgado-Esteban M, ..., Bolanos JP, Almeida A 0 2008/10/01
18768753The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice.Mol Biol Cell, 2008 Sep 3; [Epub ahead of print]Sou YS, Waguri S, ..., Tanaka K, Komatsu M 0 2008/09/30
18768752An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure.Mol Biol Cell, 2008 Sep 3; [Epub ahead of print]Fujita N, Hayashi M, ..., Noda T, Yoshimori T 0 2008/09/29
18725538Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.J Cell Biol, 2008 Aug 25;182(4);685-701, Axe EL, Walker SA, ..., Griffiths G, Ktistakis NT 2 2008/09/05
18691969Ubc9 sumoylation regulates SUMO target discrimination.Mol Cell, 2008 Aug 8;31(3);371-82, Knipscheer P, Flotho A, ..., Sixma TK, Pichler A 0 2008/09/04
18701681Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.J Neurosci, 2008 Aug 13;28(33);8189-98, Bedford L, Hay D, ..., Lowe J, Mayer RJ 0 2008/09/01
18701704Piecemeal Microautophagy of the Nucleus Requires the Core Macroautophagy Genes.Mol Biol Cell, 2008 Aug 13; [Epub ahead of print]Krick R, Muehe Y, ..., Goldfarb DS, Thumm M 0 2008/08/29
18485871Epigenetic control of rDNA loci in response to intracellular energy status.Cell, 2008 May 16;133(4);627-39, Murayama A, Ohmori K, ..., Shimizu T, Yanagisawa J 0 2008/08/25
18625846Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy.J Cell Biol, 2008 Jul 14;182(1);129-40, Geng J, Baba M, Nair U, Klionsky DJ 1 2008/08/20
18701890Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.Nature, 2008 Aug 13; [Epub ahead of print]Nedjic J, Aichinger M, ..., Mizushima N, Klein L 0 2008/08/19
18508918Atg8 Controls Phagophore Expansion during Autophagosome Formation.Mol Biol Cell, 2008 Aug;19(8);3290-8, Xie Z, Nair U, Klionsky DJ 0 2008/08/19
18508924Ubc4/5 and c-Cbl Continue to Ubiquitinate EGF Receptor after Internalization to Facilitate Polyubiquitination and Degradation.Mol Biol Cell, 2008 May 28; [Epub ahead of print]Umebayashi K, Stenmark H, Yoshimori T 0 2008/07/30
18550769The C-terminal PAL motif and transmembrane domain 9 of presenilin 1 are involved in the formation of the catalytic pore of the gamma-secretase.J Neurosci, 2008 Jun 11;28(24);6264-71, Sato C, Takagi S, Tomita T, Iwatsubo T 0 2008/07/18
18570871JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy.Mol Cell, 2008 Jun 20;30(6);678-88, Wei Y, Pattingre S, ..., Bassik M, Levine B 2 2008/07/15
17767160T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.Nat Immunol, 2007 Oct;8(10);1067-75, Tanaka Y, Hamano S, ..., Sasazuki T, Fukui Y 0 2008/07/12
18567580Ubiquitin ligase Smurf1 mediates TNF-induced systemic bone loss by promoting proteasomal degradation of BMP signaling proteins.J Biol Chem, 2008 Jun 19; [Epub ahead of print]Guo R, Yamashita M, ..., Boyce BF, Xing L 0 2008/07/11
18187572Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury.Am J Pathol, 2008 Feb;172(2);454-69, Koike M, Shibata M, ..., Tanaka K, Uchiyama Y 0 2008/07/08
184451Environmental influences on pituitary-adrenal system function.Probl Actuels Endocrinol Nutr, 1975;55-62, Bohus B 0 2008/07/08
18258863Synaptic protein degradation underlies destabilization of retrieved fear memory.Science, 2008 Feb 29;319(5867);1253-6, Lee SH, Choi JH, ..., Kim H, Kaang BK 0 2008/07/08
18591426Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells.J Cell Biol, 2008 Jun 30;181(7);1065-72, Hashimoto D, Ohmuraya M, ..., Mizushima N, Yamamura K 0 2008/07/07
18599786Autophagy Is Essential for Preimplantation Development of Mouse Embryos.Science, 2008 Jul 4;321(5885);117-120, Tsukamoto S, Kuma A, ..., Yamamoto A, Mizushima N 1 2008/07/07
17765686Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila.Dev Cell, 2007 Sep;13(3);446-54, Xue L, Igaki T, ..., Miura M, Xu T 0 2008/07/04
17679695Local initiation of caspase activation in Drosophila salivary gland programmed cell death in vivo.Proc Natl Acad Sci U S A, 2007 Aug 14;104(33);13367-72, Takemoto K, Kuranaga E, ..., Miyawaki A, Miura M 0 2008/07/03
18166655DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells.J Cell Biol, 2007 Dec 31;179(7);1467-80, Ribeiro PS, Kuranaga E, ..., Miura M, Meier P 0 2008/07/03
17872946Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation.J Biol Chem, 2007 Nov 23;282(47);33908-14, Ballar P, Zhong Y, ..., Shen Y, Fang S 0 2008/07/03
18544539Regulation of calpain activity by c-myc through calpastatin and promotion of transformation in c-myc-negative cells by calpastatin suppression.J Biol Chem, 2008 Jun 10; [Epub ahead of print]Niapour M, Yu Y, Berger SA 0 2008/07/02
18524774Structural basis for sorting mechanism of p62 in selective autophagy.J Biol Chem, 2008 Jun 4; [Epub ahead of print]Ichimura Y, Kumanomidou T, ..., Tanaka K, Komatsu M 0 2008/07/02
18552835Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.Nat Cell Biol, 2008 Jun 15; [Epub ahead of print]Liang C, Lee JS, ..., Akazawa C, Jung JU 2 2008/06/30
18424911Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation.Autophagy, 2008 Sep-Oct;4(5);692-700, Ueno T, Sato W, ..., Watanabe S, Kominami E 0 2008/06/28
18544538Physiological pH and acidic phospholipids contribute to substrate specificity in lipidation of Atg8.J Biol Chem, 2008 Jun 10; [Epub ahead of print]Oh-Oka K, Nakatogawa H, Ohsumi Y 0 2008/06/25
18502753Human XTP3-B forms an ER quality-control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.J Biol Chem, 2008 May 23; [Epub ahead of print]Hosokawa N, Wada I, ..., Okawa K, Nagata K 0 2008/06/10
18448665Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation.Mol Biol Cell, 2008 Apr 30; [Epub ahead of print]Itoh T, Fujita N, ..., Yoshimori T, Fukuda M 2 2008/05/31
18171922Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance.J Neurosci, 2008 Jan 2;28(1);50-9, Meller R, Thompson SJ, ..., Xiong ZG, Simon RP 0 2008/05/31
18354483SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.Nature, 2008 Mar 20;452(7185);370-4, Westbrook TF, Hu G, ..., Harper JW, Elledge SJ 0 2008/05/29
18443221FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.J Cell Biol, 2008 May 5;181(3);497-510, Hara T, Takamura A, ..., Guan JL, Mizushima N 0 2008/05/22
18424433The COP9/signalosome increases the efficiency of pVHL ubiquitin ligase-mediated hypoxia inducible factor-alpha ubiquitination.J Biol Chem, 2008 Apr 18; [Epub ahead of print]Miyauchi Y, Kato M, Tokunaga F, Iwai K 0 2008/05/19
17978089Regulation of rtt107 recruitment to stalled DNA replication forks by the cullin rtt101 and the rtt109 acetyltransferase.Mol Biol Cell, 2008 Jan;19(1);171-80, Roberts TM, Zaidi IW, ..., Peter M, Brown GW 0 2008/05/17
18454133Essential role for Nix in autophagic maturation of erythroid cells.Nature, 2008 May 4; [Epub ahead of print]Sandoval H, Thiagarajan P, ..., Chen M, Wang J 0 2008/05/13
18316613Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy.Cancer Res, 2008 Mar 1;68(5);1485-94, Apel A, Herr I, ..., Rodemann HP, Mayer A 0 2008/05/02
17506859p25/cyclin-dependent kinase 5 promotes the progression of cell death in nucleus of endoplasmic reticulum-stressed neurons.J Neurochem, 2007 Jul;102(1);133-40, Saito T, Konno T, ..., Ishiguro K, Hisanaga S 0 2008/04/28
18329368Active caspase-1 is a regulator of unconventional protein secretion.Cell, 2008 Mar 7;132(5);818-31, Keller M, Ruegg A, Werner S, Beer HD 2 2008/04/25
18376137Utilizing flow cytometry to monitor autophagy in living mammalian cells.Autophagy, 2008 Mar 20;4(5); [Epub ahead of print]Shvets E, Fass E, Elazar Z 0 2008/04/23
18391941Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease.Nat Cell Biol, 2008 Apr 6; [Epub ahead of print]Kraft C, Deplazes A, Sohrmann M, Peter M 0 2008/04/15
18331717PpAtg30 Tags Peroxisomes for Turnover by Selective Autophagy.Dev Cell, 2008 Mar;14(3);365-76, Farre JC, Manjithaya R, Mathewson RD, Subramani S 2 2008/04/02
18344973Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.EMBO Rep, 2008 Mar 14; [Epub ahead of print]Torashima T, Koyama C, ..., Yamaguchi H, Hirai H 0 2008/04/01
17608927c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.BMC Cell Biol, 2007;27, Ciani L, Salinas PC 0 2008/04/01
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17687326Global changes to the ubiquitin system in Huntington's disease.Nature, 2007 Aug 9;448(7154);704-8, Bennett EJ, Shaler TA, ..., Schulman H, Kopito RR 0 2007/09/04
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17709747The Atg5 Atg12 conjugate associates with innate antiviral immune responses.Proc Natl Acad Sci U S A, 2007 Aug 20; [Epub ahead of print]Jounai N, Takeshita F, ..., Suzuki K, Okuda K 2 2007/09/01
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17185560A "silent" polymorphism in the MDR1 gene changes substrate specificity.Science, 2007 Jan 26;315(5811);525-8, Kimchi-Sarfaty C, Oh JM, ..., Ambudkar SV, Gottesman MM 1 2007/08/23
17560372Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.Mol Cell, 2007 Jun 8;26(5);663-74, Urban J, Soulard A, ..., Hall MN, Loewith R 1 2007/08/22
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17499388Refining dermatology journal impact factors using PageRank.J Am Acad Dermatol, 2007 Jul;57(1);116-9, Dellavalle RP, Schilling LM, ..., Van de Sompel H, Bollen J 0 2007/08/15
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17632063Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion.Cell, 2007 Jul 13;130(1);165-78, Nakatogawa H, Ichimura Y, Ohsumi Y 1 2007/08/02
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17589504Ambra1 regulates autophagy and development of the nervous system.Nature, 2007 Jun 24; [Epub ahead of print]Maria Fimia G, Stoykova A, ..., Chowdhury K, Cecconi F 2 2007/07/26
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17386266PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.Mol Cell, 2007 Mar 23;25(6);903-15, Sancak Y, Thoreen CC, ..., Carr SA, Sabatini DM 0 2007/06/14
17540904Regulation of CD8+ T cell development by thymus-specific proteasomes.Science, 2007 Jun 1;316(5829);1349-53, Murata S, Sasaki K, ..., Takahama Y, Tanaka K 0 2007/06/03
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17016471Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF.EMBO J, 2006 Oct 4;25(19);4547-56, Tafforeau L, Le Blastier S, ..., Vandenhaute J, Hermand D 0 2007/05/01
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17136098Specialized hepatocyte-like cells regulate Drosophila lipid metabolism.Nature, 2007 Jan 18;445(7125);275-80, Gutierrez E, Wiggins D, Fielding B, Gould AP 0 2007/03/30
17218261Ubiquitination regulates PTEN nuclear import and tumor suppression.Cell, 2007 Jan 12;128(1);141-56, Trotman LC, Wang X, ..., Jiang X, Pandolfi PP 0 2007/03/30
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17132049Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response.PLoS Biol, 2006 Nov;4(12);e423, Bernales S, McDonald KL, Walter P 0 2007/02/13
17237771The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis.Nat Cell Biol, 2007 Feb;9(2);218-24, Liang J, Shao SH, ..., Slingerland JM, Mills GB 1 2007/02/11
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17101693Calpain is required for macroautophagy in mammalian cells.J Cell Biol, 2006 Nov 20;175(4);595-605, Demarchi F, Bertoli C, ..., Eskelinen EL, Schneider C 1 2007/02/05
16424905A novel ubiquitin-binding protein ZNF216 functioning in muscle atrophy.EMBO J, 2006 Feb 8;25(3);554-64, Hishiya A, Iemura S, ..., Ikeda K, Watanabe K 0 2007/01/25
16982691Regulation of the M-cadherin-beta-catenin complex by calpain 3 during terminal stages of myogenic differentiation.Mol Cell Biol, 2006 Nov;26(22);8437-47, Kramerova I, Kudryashova E, Wu B, Spencer MJ 0 2007/01/24
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17210638Calpain 6 Is Involved in Microtubule Stabilization and Cytoskeletal Organization.Mol Cell Biol, 2007 Jan 8; [Epub ahead of print]Tonami K, Kurihara Y, ..., Asano T, Kurihara H 0 2007/01/16
17200669A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.Nat Genet, 2006 Dec 31; [Epub ahead of print]Hampe J, Franke A, ..., Krawczak M, Schreiber S 0 2007/01/15
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16492811The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover.J Cell Biol, 2006 Feb 27;172(5);693-704, Duex JE, Tang F, Weisman LS 0 2007/01/12
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17086191Resveratrol improves health and survival of mice on a high-calorie diet.Nature, 2006 Nov 16;444(7117);337-42, Baur JA, Pearson KJ, ..., de Cabo R, Sinclair DA 0 2006/12/22
17053147S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth.Science, 2006 Oct 20;314(5798);467-71, Dorrello NV, Peschiaroli A, ..., Sherman NE, Pagano M 0 2006/12/22
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16962653SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.Cell, 2006 Oct 6;127(1);125-37, Jacinto E, Facchinetti V, ..., Qin J, Su B 0 2006/12/22
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