Proteolysis Forum
since 2009.04.08

プロテオリシスフォーラムの新規投稿機能は停止しました。長年のご利用ありがとうございました。
関連論文に関する情報やコメントの投稿は、ユビキチンフォーラム、オートファジーフォーラムにお願いします。

   スレッド一覧
全463件中　301-350件表示
1 2 3 4 5 6 7 8 9 10
PubMedID Title Journal Author Re updated
18722006Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini.Cell, 2008 Sep 5;134(5);866-76, Mahrus S, Trinidad JC, ..., Burlingame AL, Wells JA 0 2009/01/14
19117993BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.Cancer Res, 2009 Jan 1;69(1);111-9, Nishikawa H, Wu W, ..., Fukuda M, Ohta T 0 2009/01/08
19088090Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of {beta}-catenin/Arm and stimulation of target gene expression.Development, 2009 Jan;136(2);241-51, Lee W, Swarup S, ..., Ishitani T, Verheyen EM 0 2009/01/07
19119233Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy.Science, 2009 Jan 2;323(5910);124-7, Yang Q, She H, ..., Shacka JJ, Mao Z 0 2009/01/07
18832610Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.Science, 2008 Nov 14;322(5904);1104-7, Pearce MJ, Mintseris J, ..., Gygi SP, Darwin KH 0 2008/12/15
19050071Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase.Proc Natl Acad Sci U S A, 2008 Dec 2; [Epub ahead of print]Sun Q, Fan W, ..., Chen S, Zhong Q 0 2008/12/05
19029340Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.J Cell Biol, 2008 Nov 24; [Epub ahead of print]Narendra D, Tanaka A, Suen DF, Youle RJ 3 2008/12/04
19021777Structural basis of target recognition by Atg8/LC3 during selective autophagy.Genes Cells, 2008 Oct 22; [Epub ahead of print]Noda NN, Kumeta H, ..., Ohsumi Y, Inagaki F 0 2008/12/03
18997778Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.Nat Struct Mol Biol, 2008 Nov 9; [Epub ahead of print]Singer AU, Rohde JR, ..., Parsot C, Savchenko A 0 2008/12/03
19020622Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.Nature, 2008 Nov 20;456(7220);404-408, Moldoveanu T, Gehring K, Green DR 1 2008/11/30
19020623Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin.Nature, 2008 Nov 20;456(7220);409-12, Hanna RA, Campbell RL, Davies PL 0 2008/11/29
18757741Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.Proc Natl Acad Sci U S A, 2008 Sep 9;105(36);13568-73, Shibata T, Ohta T, ..., Yamamoto M, Hirohashi S 0 2008/11/24
18829864Self-Interaction Is Critical for Atg9 Transport and Function at the Phagophore Assembly Site during Autophagy.Mol Biol Cell, 2008 Oct 1; [Epub ahead of print]He C, Baba M, Cao Y, Klionsky DJ 1 2008/11/19
18948269RalA functions as an indispensable signal mediator for nutrient sensing system.J Biol Chem, 2008 Oct 23; [Epub ahead of print]Maehama T, Tanaka M, ..., Kanaho Y, Hanada K 0 2008/11/18
18716223Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli.J Neurosci, 2008 Aug 20;28(34);8644-54, Purro SA, Ciani L, ..., Siomou E, Salinas PC 0 2008/11/14
18812319Isolation of hyperactive mutants of mammalian target of rapamycin.J Biol Chem, 2008 Sep 23; [Epub ahead of print]Ohne Y, Takahara T, ..., Mizushima N, Maeda T 0 2008/11/10
18948957Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors.Nature, 2008 Oct 23;455(7216);1134-7, Kim HJ, Oh SA, ..., Twell D, Nam HG 0 2008/11/05
18936157Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domain using an Atg13-independent mechanism.Mol Cell Biol, 2008 Oct 20; [Epub ahead of print]Chan EY, Longatti A, McKnight NC, Tooze SA 0 2008/11/05
18353967Ubiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion.Mol Biol Cell, 2008 Jun;19(6);2457-64, Cohen MM, Leboucher GP, ..., Glickman MH, Weissman AM 0 2008/10/31
18940611Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism.Structure, 2008 Oct;16(10);1562-73, Suzuki H, Kawasaki M, ..., Wakatsuki S, Maki M 0 2008/10/27
18843052Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG.Mol Biol Cell, 2008 Oct 8; [Epub ahead of print]Itakura E, Kishi C, Inoue K, Mizushima N 4 2008/10/23
0;  1 2008/10/21
18849965Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.Nature, 2008 Oct 5; [Epub ahead of print]Saitoh T, Fujita N, ..., Yoshimori T, Akira S 0 2008/10/20
18818209Mitophagy in yeast occurs through a selective mechanism.J Biol Chem, 2008 Sep 25; [Epub ahead of print]Kanki T, Klionsky DJ 0 2008/10/20
18662542Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes.Cell, 2008 Jul 25;134(2);268-78, Lee I, Schindelin H 0 2008/10/14
18756251Misfolded proteins partition between two distinct quality control compartments.Nature, 2008 Aug 28;454(7208);1088-95, Kaganovich D, Kopito R, Frydman J 0 2008/10/02
18818692Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity.EMBO J, 2008 Sep 25; [Epub ahead of print]Maestre C, Delgado-Esteban M, ..., Bolanos JP, Almeida A 0 2008/10/01
18768753The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice.Mol Biol Cell, 2008 Sep 3; [Epub ahead of print]Sou YS, Waguri S, ..., Tanaka K, Komatsu M 0 2008/09/30
18768752An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure.Mol Biol Cell, 2008 Sep 3; [Epub ahead of print]Fujita N, Hayashi M, ..., Noda T, Yoshimori T 0 2008/09/29
18725538Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.J Cell Biol, 2008 Aug 25;182(4);685-701, Axe EL, Walker SA, ..., Griffiths G, Ktistakis NT 2 2008/09/05
18691969Ubc9 sumoylation regulates SUMO target discrimination.Mol Cell, 2008 Aug 8;31(3);371-82, Knipscheer P, Flotho A, ..., Sixma TK, Pichler A 0 2008/09/04
18701681Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.J Neurosci, 2008 Aug 13;28(33);8189-98, Bedford L, Hay D, ..., Lowe J, Mayer RJ 0 2008/09/01
18701704Piecemeal Microautophagy of the Nucleus Requires the Core Macroautophagy Genes.Mol Biol Cell, 2008 Aug 13; [Epub ahead of print]Krick R, Muehe Y, ..., Goldfarb DS, Thumm M 0 2008/08/29
18485871Epigenetic control of rDNA loci in response to intracellular energy status.Cell, 2008 May 16;133(4);627-39, Murayama A, Ohmori K, ..., Shimizu T, Yanagisawa J 0 2008/08/25
18625846Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy.J Cell Biol, 2008 Jul 14;182(1);129-40, Geng J, Baba M, Nair U, Klionsky DJ 1 2008/08/20
18701890Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.Nature, 2008 Aug 13; [Epub ahead of print]Nedjic J, Aichinger M, ..., Mizushima N, Klein L 0 2008/08/19
18508918Atg8 Controls Phagophore Expansion during Autophagosome Formation.Mol Biol Cell, 2008 Aug;19(8);3290-8, Xie Z, Nair U, Klionsky DJ 0 2008/08/19
18508924Ubc4/5 and c-Cbl Continue to Ubiquitinate EGF Receptor after Internalization to Facilitate Polyubiquitination and Degradation.Mol Biol Cell, 2008 May 28; [Epub ahead of print]Umebayashi K, Stenmark H, Yoshimori T 0 2008/07/30
18550769The C-terminal PAL motif and transmembrane domain 9 of presenilin 1 are involved in the formation of the catalytic pore of the gamma-secretase.J Neurosci, 2008 Jun 11;28(24);6264-71, Sato C, Takagi S, Tomita T, Iwatsubo T 0 2008/07/18
18570871JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy.Mol Cell, 2008 Jun 20;30(6);678-88, Wei Y, Pattingre S, ..., Bassik M, Levine B 2 2008/07/15
17767160T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.Nat Immunol, 2007 Oct;8(10);1067-75, Tanaka Y, Hamano S, ..., Sasazuki T, Fukui Y 0 2008/07/12
18567580Ubiquitin ligase Smurf1 mediates TNF-induced systemic bone loss by promoting proteasomal degradation of BMP signaling proteins.J Biol Chem, 2008 Jun 19; [Epub ahead of print]Guo R, Yamashita M, ..., Boyce BF, Xing L 0 2008/07/11
18187572Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury.Am J Pathol, 2008 Feb;172(2);454-69, Koike M, Shibata M, ..., Tanaka K, Uchiyama Y 0 2008/07/08
184451Environmental influences on pituitary-adrenal system function.Probl Actuels Endocrinol Nutr, 1975;55-62, Bohus B 0 2008/07/08
18258863Synaptic protein degradation underlies destabilization of retrieved fear memory.Science, 2008 Feb 29;319(5867);1253-6, Lee SH, Choi JH, ..., Kim H, Kaang BK 0 2008/07/08
18591426Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells.J Cell Biol, 2008 Jun 30;181(7);1065-72, Hashimoto D, Ohmuraya M, ..., Mizushima N, Yamamura K 0 2008/07/07
18599786Autophagy Is Essential for Preimplantation Development of Mouse Embryos.Science, 2008 Jul 4;321(5885);117-120, Tsukamoto S, Kuma A, ..., Yamamoto A, Mizushima N 1 2008/07/07
17765686Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila.Dev Cell, 2007 Sep;13(3);446-54, Xue L, Igaki T, ..., Miura M, Xu T 0 2008/07/04
17679695Local initiation of caspase activation in Drosophila salivary gland programmed cell death in vivo.Proc Natl Acad Sci U S A, 2007 Aug 14;104(33);13367-72, Takemoto K, Kuranaga E, ..., Miyawaki A, Miura M 0 2008/07/03
18166655DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells.J Cell Biol, 2007 Dec 31;179(7);1467-80, Ribeiro PS, Kuranaga E, ..., Miura M, Meier P 0 2008/07/03
17872946Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation.J Biol Chem, 2007 Nov 23;282(47);33908-14, Ballar P, Zhong Y, ..., Shen Y, Fang S 0 2008/07/03
18544539Regulation of calpain activity by c-myc through calpastatin and promotion of transformation in c-myc-negative cells by calpastatin suppression.J Biol Chem, 2008 Jun 10; [Epub ahead of print]Niapour M, Yu Y, Berger SA 0 2008/07/02
18524774Structural basis for sorting mechanism of p62 in selective autophagy.J Biol Chem, 2008 Jun 4; [Epub ahead of print]Ichimura Y, Kumanomidou T, ..., Tanaka K, Komatsu M 0 2008/07/02
18552835Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.Nat Cell Biol, 2008 Jun 15; [Epub ahead of print]Liang C, Lee JS, ..., Akazawa C, Jung JU 2 2008/06/30
18424911Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation.Autophagy, 2008 Sep-Oct;4(5);692-700, Ueno T, Sato W, ..., Watanabe S, Kominami E 0 2008/06/28
18544538Physiological pH and acidic phospholipids contribute to substrate specificity in lipidation of Atg8.J Biol Chem, 2008 Jun 10; [Epub ahead of print]Oh-Oka K, Nakatogawa H, Ohsumi Y 0 2008/06/25
18502753Human XTP3-B forms an ER quality-control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.J Biol Chem, 2008 May 23; [Epub ahead of print]Hosokawa N, Wada I, ..., Okawa K, Nagata K 0 2008/06/10
18448665Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation.Mol Biol Cell, 2008 Apr 30; [Epub ahead of print]Itoh T, Fujita N, ..., Yoshimori T, Fukuda M 2 2008/05/31
18171922Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance.J Neurosci, 2008 Jan 2;28(1);50-9, Meller R, Thompson SJ, ..., Xiong ZG, Simon RP 0 2008/05/31
18354483SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.Nature, 2008 Mar 20;452(7185);370-4, Westbrook TF, Hu G, ..., Harper JW, Elledge SJ 0 2008/05/29
18443221FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.J Cell Biol, 2008 May 5;181(3);497-510, Hara T, Takamura A, ..., Guan JL, Mizushima N 0 2008/05/22
18424433The COP9/signalosome increases the efficiency of pVHL ubiquitin ligase-mediated hypoxia inducible factor-alpha ubiquitination.J Biol Chem, 2008 Apr 18; [Epub ahead of print]Miyauchi Y, Kato M, Tokunaga F, Iwai K 0 2008/05/19
17978089Regulation of rtt107 recruitment to stalled DNA replication forks by the cullin rtt101 and the rtt109 acetyltransferase.Mol Biol Cell, 2008 Jan;19(1);171-80, Roberts TM, Zaidi IW, ..., Peter M, Brown GW 0 2008/05/17
18454133Essential role for Nix in autophagic maturation of erythroid cells.Nature, 2008 May 4; [Epub ahead of print]Sandoval H, Thiagarajan P, ..., Chen M, Wang J 0 2008/05/13
18316613Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy.Cancer Res, 2008 Mar 1;68(5);1485-94, Apel A, Herr I, ..., Rodemann HP, Mayer A 0 2008/05/02
17506859p25/cyclin-dependent kinase 5 promotes the progression of cell death in nucleus of endoplasmic reticulum-stressed neurons.J Neurochem, 2007 Jul;102(1);133-40, Saito T, Konno T, ..., Ishiguro K, Hisanaga S 0 2008/04/28
18329368Active caspase-1 is a regulator of unconventional protein secretion.Cell, 2008 Mar 7;132(5);818-31, Keller M, Ruegg A, Werner S, Beer HD 2 2008/04/25
18376137Utilizing flow cytometry to monitor autophagy in living mammalian cells.Autophagy, 2008 Mar 20;4(5); [Epub ahead of print]Shvets E, Fass E, Elazar Z 0 2008/04/23
18391941Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease.Nat Cell Biol, 2008 Apr 6; [Epub ahead of print]Kraft C, Deplazes A, Sohrmann M, Peter M 0 2008/04/15
18331717PpAtg30 Tags Peroxisomes for Turnover by Selective Autophagy.Dev Cell, 2008 Mar;14(3);365-76, Farre JC, Manjithaya R, Mathewson RD, Subramani S 2 2008/04/02
18344973Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.EMBO Rep, 2008 Mar 14; [Epub ahead of print]Torashima T, Koyama C, ..., Yamaguchi H, Hirai H 0 2008/04/01
17608927c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.BMC Cell Biol, 2007;27, Ciani L, Salinas PC 0 2008/04/01
18310072Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.J Biol Chem, 2008 Feb 29; [Epub ahead of print]Hayashi C, Ono Y, ..., Labeit S, Sorimachi H 0 2008/03/31
17517623Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.Proc Natl Acad Sci U S A, 2007 May 29;104(22);9511-6, Luo W, Dou F, ..., Greengard P, Chiosis G 0 2008/03/27
18337468Constitutive Activation of Chaperone-mediated Autophagy in Cells with Impaired Macroautophagy.Mol Biol Cell, 2008 Mar 12; [Epub ahead of print]Kaushik S, Massey AC, Mizushima N, Cuervo AM 1 2008/03/26
18296641A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.Proc Natl Acad Sci U S A, 2008 Mar 4;105(9);3374-9, Lee IH, Cao L, ..., Alt FW, Finkel T 0 2008/03/21
18278057Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes.Nat Struct Mol Biol, 2008 Mar;15(3);228-36, Yashiroda H, Mizushima T, ..., Yamane T, Tanaka K 0 2008/03/21
18321988The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy.Mol Biol Cell, 2008 Mar 5; [Epub ahead of print]Fujita N, Itoh T, ..., Noda T, Yoshimori T 1 2008/03/19
18332441Confinement of caspase-12 proteolytic activity to autoprocessing.Proc Natl Acad Sci U S A, 2008 Mar 10; [Epub ahead of print]Roy S, Sharom JR, ..., Saleh M, Nicholson DW 0 2008/03/18
17673661Quantitative mass spectrometry identifies insulin signaling targets in C. elegans.Science, 2007 Aug 3;317(5838);660-3, Dong MQ, Venable JD, ..., Dillin A, Yates JR 1 2008/03/14
18287526Organization of the Pre-Autophagosomal Structure Responsible for Autophagosome Formation.Mol Biol Cell, 2008 Feb 20; [Epub ahead of print]Kawamata T, Kamada Y, ..., Sekito T, Ohsumi Y 3 2008/03/14
17673525Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone.Stem Cells, 2007 Nov;25(11);2827-36, Adachi K, Mirzadeh Z, ..., Okano H, Sawamoto K 0 2008/03/14
18083104Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.Cell, 2007 Dec 14;131(6);1149-63, Komatsu M, Waguri S, ..., Kominami E, Tanaka K 4 2008/03/12
17382888Proteolytic degradation of SCOP in the hippocampus contributes to activation of MAP kinase and memory.Cell, 2007 Mar 23;128(6);1219-29, Shimizu K, Phan T, Mansuy IM, Storm DR 0 2008/03/12
18000393Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls.Autophagy, 2008 Jan-Feb;4(1);131-4, Tanida I, Yamaji T, ..., Kominami E, Hanada K 0 2008/03/10
18249191Comprehensive proteomics analysis of autophagy-deficient mouse liver.Biochem Biophys Res Commun, 2008 Apr 11;368(3);643-9, Matsumoto N, Ezaki J, ..., Tanaka K, Kominami E 0 2008/03/07
18298591Irs4p and Tax4p: Two Redundant EH Domain Proteins Involved in Autophagy.Traffic, 2008 Feb 21; [Epub ahead of print]Bugnicourt A, Mari M, ..., Haguenauer-Tsapis R, Galan JM 4 2008/03/07
18316332Human calpain 7/PalBH associates with a subset of ESCRT-III-related proteins in its N-terminal region and partly localizes to endocytic membrane compartments.J Biochem, 2008 Mar 3; [Epub ahead of print]Yorikawa C, Takaya E, ..., Shibata H, Maki M 0 2008/03/06
18287533Arp2 links Autophagic Machinery with the Actin Cytoskeleton.Mol Biol Cell, 2008 Feb 20; [Epub ahead of print]Monastyrska I, He C, ..., Li Z, Klionsky DJ 1 2008/03/03
17646163Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains.J Biol Chem, 2007 Sep 21;282(38);27847-56, Hata S, Doi N, Kitamura F, Sorimachi H 0 2008/03/01
18281291Mitochondrial autophagy is a HIF-1-dependent adaptive metabolic response to hypoxia.J Biol Chem, 2008 Feb 15; [Epub ahead of print]Zhang H, Bosch-Marce M, ..., Gonzalez FJ, Semenza GL 0 2008/02/29
17607357Dysferlin-mediated membrane repair protects the heart from stress-induced left ventricular injury.J Clin Invest, 2007 Jul;117(7);1805-13, Han R, Bansal D, ..., McNeil PL, Campbell KP 0 2008/02/29
17371879Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.J Biol Chem, 2007 May 11;282(19);14493-504, Ojima K, Ono Y, ..., Labeit S, Sorimachi H 0 2008/02/29
18222470Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.J Mol Biol, 2008 Mar 7;376(5);1224-36, Koyama S, Hata S, ..., Labeit S, Sorimachi H 0 2008/02/29
17373644Comprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94.Biotechnol J, 2007 May;2(5);565-76, Ono Y, Hayashi C, ..., Yanagida M, Sorimachi H 0 2008/02/28
18258189The importance of conserved amino acid residues in p94 protease sub-domain IIb and the IS2 region for constitutive autolysis.FEBS Lett, 2008 Mar 5;582(5);691-8, Ono Y, Hayashi C, ..., Tagami M, Sorimachi H 0 2008/02/28
17627283XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway.EMBO J, 2007 Aug 8;26(15);3592-606, Lee RH, Iioka H, ..., Natsume T, Kinoshita N 0 2008/02/28
18070881N terminus of calpain 1 is a mitochondrial targeting sequence.J Biol Chem, 2008 Feb 8;283(6);3409-17, Badugu R, Garcia M, ..., Joshi A, Geddes JW 0 2008/02/27
18264111Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.Nat Struct Mol Biol, 2008 Feb 10; [Epub ahead of print]Huang DT, Zhuang M, Ayrault O, Schulman BA 0 2008/02/27
17713477Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.Nature, 2007 Sep 13;449(7159);248-51, Jia D, Jurkowska RZ, ..., Jeltsch A, Cheng X 0 2008/02/19
18200046Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.EMBO J, 2008 Jan 23;27(2);433-46, Twig G, Elorza A, ..., Corkey BE, Shirihai OS 1 2008/02/19
18039653Autophagy is involved in nutritional stress response and differentiation in Trypanosoma cruzi.J Biol Chem, 2007 Nov 26; [Epub ahead of print]Alvarez VE, Kosec G, ..., Cazzulo JJ, Turk B 0 2007/12/10
18056421Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.Genes Dev, 2007 Dec 1;21(23);3061-6, Juhasz G, Erdi B, Sass M, Neufeld TP 0 2007/12/10
17984323Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.J Cell Biol, 2007 Nov 5;179(3);485-500, Filimonenko M, Stuffers S, ..., Stenmark H, Simonsen A 0 2007/12/10
17999726INDUCTION OF AUTOPHAGY PROMOTES FUSION OF MULTIVESICULAR BODIES WITH AUTOPHAGIC VACUOLES IN K562 CELLS.Traffic, 2007 Nov 12; [Epub ahead of print]Fader CM, Sanchez D, Furlan M, Colombo MI 0 2007/11/21
17952025Genetic interactions between Drosophila melanogaster Atg1 and paxillin reveal a role for paxillin in autophagosome formation.Autophagy, 2007 Oct 8;4(1); [Epub ahead of print]Chen GC, Lee JY, ..., Thomas SM, Settleman J 0 2007/11/15
17991864Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.Science, 2007 Nov 9;318(5852);977-80, Bai X, Ma D, ..., Liu Y, Jiang Y 0 2007/11/12
17911112Evidence for the direct involvement of the proteasome in the proteolytic processing of the Aspergillus nidulans zinc-finger transcription factor PACC.J Biol Chem, 2007 Oct 1; [Epub ahead of print]Hervas-Aguilar A, Rodriguez JM, ..., Arst HN, Penalva MA 0 2007/10/09
17891140Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.Nat Cell Biol, 2007 Sep 23; [Epub ahead of print]Takahashi Y, Coppola D, ..., Pledger WJ, Wang HG 1 2007/10/09
17828264Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans.Nat Genet, 2007 Sep 9; [Epub ahead of print]Macarthur DG, Seto JT, ..., Yang N, North KN 0 2007/09/27
17699586Protein Kinase A and Sch9 Cooperatively Regulate Induction of Autophagy in Saccharomyces cerevisiae.Mol Biol Cell, 2007 Aug 15; [Epub ahead of print]Yorimitsu T, Zaman S, Broach JR, Klionsky DJ 2 2007/09/19
17687326Global changes to the ubiquitin system in Huntington's disease.Nature, 2007 Aug 9;448(7154);704-8, Bennett EJ, Shaler TA, ..., Schulman H, Kopito RR 0 2007/09/04
17726112Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration.Proc Natl Acad Sci U S A, 2007 Aug 28; [Epub ahead of print]Komatsu M, Wang QJ, ..., Tanaka K, Yue Z 0 2007/09/03
17709747The Atg5 Atg12 conjugate associates with innate antiviral immune responses.Proc Natl Acad Sci U S A, 2007 Aug 20; [Epub ahead of print]Jounai N, Takeshita F, ..., Suzuki K, Okuda K 2 2007/09/01
17699591Atg18 Regulates Organelle Morphology and Fab1 Kinase Activity Independent of Its Membrane Recruitment by Phosphatidylinositol 3,5-Bisphosphate.Mol Biol Cell, 2007 Aug 15; [Epub ahead of print]Efe JA, Botelho RJ, Emr SD 2 2007/08/30
17185560A "silent" polymorphism in the MDR1 gene changes substrate specificity.Science, 2007 Jan 26;315(5811);525-8, Kimchi-Sarfaty C, Oh JM, ..., Ambudkar SV, Gottesman MM 1 2007/08/23
17560372Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.Mol Cell, 2007 Jun 8;26(5);663-74, Urban J, Soulard A, ..., Hall MN, Loewith R 1 2007/08/22
1770723620S Proteasome Assembly Is Orchestrated by Two Distinct Pairs of Chaperones in Yeast and in Mammals.Mol Cell, 2007 Aug 17;27(4);660-74, Le Tallec B, Barrault MB, ..., Marsolier-Kergoat MC, Peyroche A 0 2007/08/22
17499388Refining dermatology journal impact factors using PageRank.J Am Acad Dermatol, 2007 Jul;57(1);116-9, Dellavalle RP, Schilling LM, ..., Van de Sompel H, Bollen J 0 2007/08/15
17541403Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation.EMBO J, 2007 Jun 20;26(12);2981-90, Wu Y, Liang S, ..., Matsui H, Tomizawa K 0 2007/08/07
17632063Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion.Cell, 2007 Jul 13;130(1);165-78, Nakatogawa H, Ichimura Y, Ohsumi Y 1 2007/08/02
17643114Cathepsin L activity controls adipogenesis and glucose tolerance.Nat Cell Biol, 2007 Jul 22; [Epub ahead of print]Yang M, Zhang Y, ..., Clement K, Shi GP 0 2007/07/26
17589504Ambra1 regulates autophagy and development of the nervous system.Nature, 2007 Jun 24; [Epub ahead of print]Maria Fimia G, Stoykova A, ..., Chowdhury K, Cecconi F 2 2007/07/26
17558393Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility.Nat Cell Biol, 2007 Jul;9(7);813-21, Iioka H, Iemura S, Natsume T, Kinoshita N 0 2007/07/09
17568747HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.Nature, 2007 Jun 14;447(7146);860-4, Pandey UB, Nie Z, ..., Baehrecke EH, Taylor JP 4 2007/06/22
17428789Phosphatidylethanolamine, a limiting factor of autophagy in yeast strains bearing a defect in the carboxypeptidase y pathway of vacuolar targeting.J Biol Chem, 2007 Jun 8;282(23);16736-43, Nebauer R, Rosenberger S, Daum G 2 2007/06/20
17335351A Caenorhabditis elegans wild type defies the temperature-size rule owing to a single nucleotide polymorphism in tra-3.PLoS Genet, 2007 Mar 2;3(3);e34, Kammenga JE, Doroszuk A, ..., Plasterk RH, Bakker J 0 2007/06/19
17386266PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.Mol Cell, 2007 Mar 23;25(6);903-15, Sancak Y, Thoreen CC, ..., Carr SA, Sabatini DM 0 2007/06/14
17540904Regulation of CD8+ T cell development by thymus-specific proteasomes.Science, 2007 Jun 1;316(5829);1349-53, Murata S, Sasaki K, ..., Takahama Y, Tanaka K 0 2007/06/03
17121849Calpain is required for the rapid, calcium-dependent repair of wounded plasma membrane.J Biol Chem, 2007 Jan 26;282(4);2567-75, Mellgren RL, Zhang W, Miyake K, McNeil PL 0 2007/06/01
17446862Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1.EMBO J, 2007 May 16;26(10);2527-2539, Maiuri MC, Le Toumelin G, ..., Geneste O, Kroemer G 0 2007/05/31
17435756Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.Nat Genet, 2007 May;39(5);596-604, Rioux JD, Xavier RJ, ..., Daly MJ, Brant SR 0 2007/05/16
17016471Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF.EMBO J, 2006 Oct 4;25(19);4547-56, Tafforeau L, Le Blastier S, ..., Vandenhaute J, Hermand D 0 2007/05/01
17347651Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4.EMBO J, 2007 Apr 4;26(7);1749-60, Scherz-Shouval R, Shvets E, ..., Gil L, Elazar Z 0 2007/04/25
17136098Specialized hepatocyte-like cells regulate Drosophila lipid metabolism.Nature, 2007 Jan 18;445(7125);275-80, Gutierrez E, Wiggins D, Fielding B, Gould AP 0 2007/03/30
17218261Ubiquitination regulates PTEN nuclear import and tumor suppression.Cell, 2007 Jan 12;128(1);141-56, Trotman LC, Wang X, ..., Jiang X, Pandolfi PP 0 2007/03/30
17277771Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.Nat Cell Biol, 2007 Mar;9(3);316-23, Haar EV, Lee SI, ..., Griffin TJ, Kim DH 1 2007/03/28
17208179Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death.Curr Biol, 2007 Jan 9;17(1);1-11, Scott RC, Juhasz G, Neufeld TP 0 2007/03/20
17192412Atg19 mediates a dual interaction cargo sorting mechanism in selective autophagy.Mol Biol Cell, 2007 Mar;18(3);919-29, Chang CY, Huang WP 0 2007/03/02
17244528Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.Mol Cell, 2007 Jan 26;25(2);193-205, Hoyer-Hansen M, Bastholm L, ..., Mathiasen IS, Jaattela M 0 2007/03/01
17256008Regulation of autophagy by the inositol trisphosphate receptor.Cell Death Differ, 2007 Jan 26; [Epub ahead of print]Criollo A, Maiuri MC, ..., Szabadkai G, Kroemer G 0 2007/03/01
17277783Ubc9 fusion-directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation.Nat Methods, 2007 Feb 4; [Epub ahead of print]Jakobs A, Koehnke J, ..., Gaestel M, Niedenthal R 0 2007/02/21
17178909Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast.J Cell Biol, 2006 Dec 18;175(6);925-35, He C, Song H, ..., Legakis JE, Klionsky DJ 0 2007/02/21
17056592A mouse model for monitoring calpain activity under physiological and pathological conditions.J Biol Chem, 2006 Dec 22;281(51);39672-80, Bartoli M, Bourg N, ..., Armande N, Richard I 1 2007/02/15
17132049Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response.PLoS Biol, 2006 Nov;4(12);e423, Bernales S, McDonald KL, Walter P 0 2007/02/13
17237771The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis.Nat Cell Biol, 2007 Feb;9(2);218-24, Liang J, Shao SH, ..., Slingerland JM, Mills GB 1 2007/02/11
17238920Efficient degradation of misfolded mutant Pma1 by endoplasmic reticulum-associated degradation requires Atg19 and the Cvt/autophagy pathway.Mol Microbiol, 2007 Feb;63(4);1069-1077, Mazon MJ, Eraso P, Portillo F 1 2007/02/11
17101693Calpain is required for macroautophagy in mammalian cells.J Cell Biol, 2006 Nov 20;175(4);595-605, Demarchi F, Bertoli C, ..., Eskelinen EL, Schneider C 1 2007/02/05
16424905A novel ubiquitin-binding protein ZNF216 functioning in muscle atrophy.EMBO J, 2006 Feb 8;25(3);554-64, Hishiya A, Iemura S, ..., Ikeda K, Watanabe K 0 2007/01/25
16982691Regulation of the M-cadherin-beta-catenin complex by calpain 3 during terminal stages of myogenic differentiation.Mol Cell Biol, 2006 Nov;26(22);8437-47, Kramerova I, Kudryashova E, Wu B, Spencer MJ 0 2007/01/24
16998475Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.Nat Cell Biol, 2006 Oct;8(10);1124-32, Yousefi S, Perozzo R, ..., Brunner T, Simon HU 2 2007/01/19
17210638Calpain 6 Is Involved in Microtubule Stabilization and Cytoskeletal Organization.Mol Cell Biol, 2007 Jan 8; [Epub ahead of print]Tonami K, Kurihara Y, ..., Asano T, Kurihara H 0 2007/01/16
17200669A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.Nat Genet, 2006 Dec 31; [Epub ahead of print]Hampe J, Franke A, ..., Krawczak M, Schreiber S 0 2007/01/15
16597703Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B.Mol Biol Cell, 2006 Jun;17(6);2674-83, Ohsaki Y, Cheng J, ..., Tokumoto T, Fujimoto T 0 2007/01/15
16917501Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy.EMBO J, 2006 Sep 6;25(17);3921-33, Kaushik S, Massey AC, Cuervo AM 0 2007/01/12
16410553Quality control of a mutant plasma membrane ATPase: ubiquitylation prevents cell-surface stability.J Cell Sci, 2006 Jan 15;119(Pt 2);360-9, Liu Y, Chang A 0 2007/01/12
16492811The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover.J Cell Biol, 2006 Feb 27;172(5);693-704, Duex JE, Tang F, Weisman LS 0 2007/01/12
16707569Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation.Mol Biol Cell, 2006 Aug;17(8);3469-83, Razi M, Futter CE 0 2006/12/23
16900101Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.Nature, 2006 Aug 31;442(7106);1058-61, Li H, Tsang CK, ..., Bertram PG, Zheng XF 0 2006/12/23
17086191Resveratrol improves health and survival of mice on a high-calorie diet.Nature, 2006 Nov 16;444(7117);337-42, Baur JA, Pearson KJ, ..., de Cabo R, Sinclair DA 0 2006/12/22
17053147S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth.Science, 2006 Oct 20;314(5798);467-71, Dorrello NV, Peschiaroli A, ..., Sherman NE, Pagano M 0 2006/12/22
17021250Atg22 recycles amino acids to link the degradative and recycling functions of autophagy.Mol Biol Cell, 2006 Dec;17(12);5094-104, Yang Z, Huang J, ..., Nair U, Klionsky DJ 0 2006/12/22
16962653SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.Cell, 2006 Oct 6;127(1);125-37, Jacinto E, Facchinetti V, ..., Qin J, Su B 0 2006/12/22
1 2 3 4 5 6 7 8 9 10

Copyright 特定領域研究「タンパク質分解による細胞・個体機能の制御」事務局